Gene Symbol | Akr1b7 |
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Entrez Gene | 11997 |
Alt Symbol | AR, Avdp, MVDP |
Species | Mouse |
Gene Type | protein-coding |
Description | aldo-keto reductase family 1, member B7 |
Other Description | aldehyde reductase|aldose reductase-related protein 1|androgen regulated vas deferens protein|vas deferens androgen-dependent protein |
Swissprots | P21300 |
Accessions | AAA39774 EDL13689 P21300 AK002705 BAB22299 AK033773 AK147775 BAE28129 BC086929 AAH86929 CN833345 J05663 AAA39773 NM_009731 NP_033861 |
Function | Reduces a broad range of aliphatic and aromatic aldehydes to the corresponding alcohols. May play a role in the metabolism of xenobiotic aromatic aldehydes (By similarity). The role of MVDP in sperm maturation and storage may be related to its potential capacity to produce fructose, or MVDP may play an osmoregulatory role by producing sorbitol. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | Pentose and glucuronate interconversions, Glycerolipid metabolism, Galactose metabolism, Fructose and mannose metabolism |
AKR1B7 CRISPR/Cas9 KO Plasmid (m) - sc-419274 from Santa Cruz Biotechnology
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AKR1B7 HDR Plasmid (m) - sc-419274-HDR from Santa Cruz Biotechnology
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AKR1B7 Double Nickase Plasmid (m) - sc-419274-NIC from Santa Cruz Biotechnology
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AKR1B7 Double Nickase Plasmid (m2) - sc-419274-NIC-2 from Santa Cruz Biotechnology
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AKR1B7 CRISPR Activation Plasmid (m) - sc-419274-ACT from Santa Cruz Biotechnology
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AKR1B7 CRISPR Activation Plasmid (m2) - sc-419274-ACT-2 from Santa Cruz Biotechnology
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AKR1B7 Lentiviral Activation Particles (m) - sc-419274-LAC from Santa Cruz Biotechnology
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AKR1B7 Lentiviral Activation Particles (m2) - sc-419274-LAC-2 from Santa Cruz Biotechnology
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AKR1B7 siRNA (m) - sc-140984 from Santa Cruz Biotechnology
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AKR1B7 shRNA Plasmid (m) - sc-140984-SH from Santa Cruz Biotechnology
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AKR1B7 shRNA (m) Lentiviral Particles - sc-140984-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU093231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26517 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26517 from Sigma-Aldrich
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AKR1B7 siRNA (Mouse) - CRM0328 from Cohesion Biosciences
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AKR1B7 - MBS8206001 from MyBioSource
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shRNA set against Mouse Akr1b7 (NM_009731.2) - SHH234474 from Creative biogene
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shRNA set against Mouse Akr1b7(NM_009731.2) - SHG050965 from Creative biogene
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AKR1B7 shRNA Plasmid (Mouse) - CHM0328 from Cohesion Biosciences
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AKR1B7 miRNA 3'UTR clone - MiUTR1M-01375 from Creative biogene
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