| Gene Symbol |
ADSSL1
|
| Entrez Gene |
100048943
|
| Alt Symbol |
ADSS1
|
| Species |
Pig
|
| Gene Type |
protein-coding
|
| Description |
adenylosuccinate synthase like 1
|
| Other Description |
AMPSase 1|IMP--aspartate ligase 1|M-type adenylosuccinate synthetase|adSS 1|adenylosuccinate synthetase isozyme 1|adenylosuccinate synthetase, basic isozyme|adenylosuccinate synthetase, muscle isozyme
|
| Swissprots |
A4Z6H0
|
| Accessions |
A4Z6H0 DQ462751 ABE73154 NM_001097509 NP_001090978
|
| Function |
Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03126}.
|
| Tissue Specificity |
Predominantly expressed in the striated muscle tissues. {ECO:0000269|PubMed:17347008}.
|
| Top Pathways |
Purine metabolism, Alanine, aspartate and glutamate metabolism
|