MTR

Gene Symbol MTR
Entrez Gene 4548
Alt Symbol HMAG, MS, cblG
Species Human
Gene Type protein-coding
Description 5-methyltetrahydrofolate-homocysteine methyltransferase
Other Description 5-methyltetrahydrofolate-homocysteine methyltransferase 1|cobalamin-dependent methionine synthase|methionine synthase|vitamin-B12 dependent methionine synthase
Swissprots Q99713 B7ZLW7 A9Z1W4 Q99707 Q99723 B9EGF7 A1L4N8
Accessions EAW70066 EAW70067 Q99707 AK090487 AK125206 AK127317 AK294270 BAG57561 AK299904 BAG61745 AK307390 AY429553 BC015894 BC067276 BC130616 AAI30617 BC136440 AAI36441 BC144095 AAI44096 BC144097 AAI44098 BC144098 BX641132 CAE46059 CB241165 DC377743 U71285 AAC51188 U73338 AAB39704 U75743 AAB58906 XM_005273141 XP_005273198 XM_006711769 XP_006711832 XM_006711770 XP_006711833 XM_011544193 XP_011542495 XM_011544194 XP_011542496 NM_000254 NP_000245 NM_001291939 NP_001278868 NM_001291940 NP_001278869
Function Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm.
Tissue Specificity Widely expressed. Expressed at the highest levels in pancreas, heart, brain, skeletal muscle and placenta. Expressed at lower levels in lung, liver and kidney.
Top Pathways Cysteine and methionine metabolism, Selenocompound metabolism, Biosynthesis of amino acids, One carbon pool by folate

MTR CRISPR/Cas9 KO Plasmid (h) - sc-410890 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR HDR Plasmid (h) - sc-410890-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR Double Nickase Plasmid (h) - sc-410890-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR Double Nickase Plasmid (h2) - sc-410890-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR CRISPR Activation Plasmid (h) - sc-410890-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR CRISPR Activation Plasmid (h2) - sc-410890-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR Lentiviral Activation Particles (h) - sc-410890-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR Lentiviral Activation Particles (h2) - sc-410890-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTR siRNA (h) - sc-78838 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTR shRNA Plasmid (h) - sc-78838-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTR shRNA (h) Lentiviral Particles - sc-78838-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTR RNAi - H00004548-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU012571 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1668 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1668 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MTR siRNA (Human) - CRH3016 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MTR (NM_000254.2) - SHH346644 from Creative biogene

Category siRNA
Species Reactivities Human

Human MTR siRNA - orb263518 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MTR shRNA Plasmid (Human) - CHH3016 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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