Enpp1

Gene Symbol	Enpp1
Entrez Gene	18605
Alt Symbol	4833416E15Rik, AI428932, C76301, CD203c, E-NPP1, Ly-41, M6S1, NPP1, Npps, PC-1, Pca, Pca-1, Pdnp1, ttw, twy
Species	Mouse
Gene Type	protein-coding
Description	ectonucleotide pyrophosphatase/phosphodiesterase 1
Other Description	1 ectonucleotide pyrophosphatase/phosphodiesterase 1|E-NPP 1|ectonucleotide pyrophosphatase/phosphodiesterase family member 1|lymphocyte antigen 41|phosphodiesterase I/nucleotide pyrophosphatase 1|phosphodiesterase I/nucleotide pyrophosphatase 1; 1 ectonucleotide pyrophosphatase/phosphodiesterase 1|plasma-cell membrane glycoprotein PC-1|tiptoe walking
Swissprots	Q924C4 P06802 Q542E9
Accessions	EDL04784 EDL04785 EDL04786 EDL04787 P06802 AF339910 AAK84174 AI428932 AK014707 AK029600 AK035402 AK036952 AK041894 BAE43316 AK088857 BAC40616 AK145233 AK164619 AK211377 BC050011 BC160371 AAI60371 J02700 AAA39893 M12552 AAA39892 XM_006512597 XP_006512660 XM_006512598 XP_006512661 XM_006512599 XP_006512662 XM_006512600 XP_006512663 NM_001308327 NP_001295256 NM_001308329 NP_001295258 NM_008813 NP_032839
Function	Appears to modulate insulin sensitivity (By similarity). By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. {ECO:0000250, ECO:0000269|PubMed:1647027, ECO:0000269|PubMed:9662402}.
Subcellular Location	Cell membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Secreted. Note=Targeted to the basolateral membrane in polarized epithelial cells and in hepatocytes, and to matrix vesicles in osteoblasts. In bile duct cells and cancer cells, located to the apical cytoplasmic side (By similarity). The proteolytically processed form is secreted. {ECO:0000250}.
Tissue Specificity	Selectively expressed on the surface of antibody-secreting cells.
Top Pathways	Purine metabolism, Nicotinate and nicotinamide metabolism, Riboflavin metabolism, Pantothenate and CoA biosynthesis, Starch and sucrose metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1), Mouse, ELISA Kit - CSB-EL007679MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, Enpp1, Mouse, ELISA Kit - E1032m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Mouse PCA-1/Yo ELISA Kit - MP0627 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Ectonucleotide Pyrophosphatase/Phosphodiesterase 1, ELISA Kit - MBS061837 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ectonucleotide pyrophosphatase/phosphodiesterase 1, ELISA Kit - MBS926662 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse ENPP1 is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.312 ng/ml-20 ng/ml.

Mouse Ectonucleotide pyrophosphatase/phosphodiesterase family member 1(ENPP1) EL - CSB-EL007679MO from Cusabio Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Mouse Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) ELISA Kit - EKC36778 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Mouse Enpp1 ELISA Kit - E051559 from Biobool Category ELISA Kit

Mouse PCA ELISA Kit - E065583 from Biobool Category ELISA Kit

ENPP1 ELISA Kit (Mouse) (OKEH05732) - OKEH05732 from Aviva Systems Biology Category ELISA Kit Prices $440.00 Sizes 96 wells Sensitivity 15.6 pg/mL Range 31.2-2,000 pg/mL

Mouse PCA-1/Yo ELISA Kit - EMP0627 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, ELISA Kit - MBS2881656 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ENPP1 ELISA Kit (Mouse) (OKCA02376) - OKCA02376 from Aviva Systems Biology Category ELISA Kit Sensitivity 0.078 ng/mL Range 0.312 - 20 ng/mL

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