NOTCH4

Gene Symbol	NOTCH4
Entrez Gene	4855
Alt Symbol	INT3
Species	Human
Gene Type	protein-coding
Description	notch 4
Other Description	Notch homolog 4|neurogenic locus notch homolog protein 4
Swissprots	Q9H3S8 B0V183 Q99458 Q5SSY7 B0V1X5 Q99466 Q9UIJ0 O00306 Q9UII9 Q99940
Accessions	AAC63097 BAA13116 BAA88951 BAA88952 BAB20317 Q99466 AK131314 AK290785 BAF83474 AK293692 BAG57129 AK294161 BAG57484 AL705928 BC033869 BC063815 AAH63815 BC140782 AAI40783 BC144540 BC144541 BQ023880 D63395 BAA09708 U95299 AAC32288 NM_004557 NP_004548
Function	Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.
Top Pathways	Notch signaling pathway, MicroRNAs in cancer, Dorso-ventral axis formation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NOTCH4 ELISA Kit (Sandwich ELISA) - LS-F12176 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.312-20 ng/ml

Neurogenic locus notch homolog protein 4, NOTCH4, Human, ELISA Kit - E2421h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Notch homolog 4 (Drosophila) , ELISA Kit - MBS900186 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 19.5 pg/ml Range 78 pg/ml-5000 pg/ml

Human Neurogenic locus notch homolog protein 4(NOTCH4) ELISA kit - CSB-EL015953HU from Cusabio Category ELISA Kit Sensitivity 19.5pg/ml Range 78 pg/ml-5000 pg/ml

Mouse NOTCH4 ELISA Kit (Custom ELISA) - LS-F19758 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

NOTCH4 - EKH4444 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

NOTCH4 ELISA Kit (Human) : 96 Wells (OKEH01648) - OKEH01648 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.1 ng/mL Range 0.312 - 20 ng/mL

Human Notch Homolog 4 (NOTCH4) ELISA Kit - EKU09420 from Biomatik Category ELISA Kit Prices $809.00, $3,557.00, $6,468.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.058 ng/mL Range 0.156-10 ng/mL

Human NOTCH4 ELISA Kit - E026798 from Biobool Category ELISA Kit Sensitivity 19.5 pg/ml

Human Neurogenic locus notch homolog protein 4 ELISA Kit - EK4517 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.34ng/mL Range 0.78-50 ng/mL

anti-Notch4 antibody [HMN4-14] - ARG23295 from Arigo Biolaboratories Category ELISA Kit

anti-Notch4 antibody [HMN4-14] (RPE) - ARG23296 from Arigo Biolaboratories Category ELISA Kit

Neurogenic locus notch homolog protein 4, ELISA Kit - MBS9428343 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Sensitivity Less than 0.1ng/mL Range 0.312-20 ng/mL

Neurogenic locus notch homolog protein 4, ELISA Kit - MBS2885287 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.312-20 ng/mL

Neurogenic locus notch homolog protein 4, ELISA Kit - MBS763320 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Notch Homolog 4 (NOTCH4) , ELISA Kit - MBS2088207 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.058ng/mL Range 0.156-10ng/mL

Human NOTCH4 ELISA Kit (Sandwich ELISA) - LS-F35804 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.188 Range 0.312-20 ng/ml

Human NOTCH4 ELISA Kit (Sandwich ELISA) - LS-F39100 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.058 Range 0.312-20 ng/ml

Human NOTCH4 ELISA Kit - orb407057 from Biorbyt Category ELISA Kit Sensitivity 19.5pg/ml Range 78 pg/ml-5000 pg/ml

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