GNAI2

Gene Symbol GNAI2
Entrez Gene 2771
Alt Symbol GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1
Species Human
Gene Type protein-coding
Description guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Other Description GTP-binding regulatory protein Gi alpha-2 chain|adenylate cyclase-inhibiting G alpha protein|guanine nucleotide-binding protein G(i) subunit alpha-2|guanine nucleotide-binding protein G(i), alpha-2 subunit
Swissprots Q8IZ71 B4E2X5 P04899 Q6B6N3 B4DYA0 B3KTZ0
Accessions AAA35894 AAD12229 AAD12230 CAA30703 EAW65051 EAW65052 EAW65053 EAW65054 EAW65055 EAW65056 P04899 AF493906 AAM12620 AK055574 BAG51536 AK096299 BAG53252 AK096595 BAG53334 AK126708 BAG54363 AK131062 AK302330 BAG63662 AK304473 BAG65287 AY677118 AAT78421 BC012138 AAH12138 BC014627 AAH14627 BC016995 AAH16995 CR456783 CAG33064 DA528337 DB044421 DQ892783 ABM83709 DQ895908 ABM86834 HY037331 J03004 AAA52556 X04828 CAA28512 NM_001166425 NP_001159897 NM_001282617 NP_001269546 NM_001282618 NP_001269547 NM_001282619 NP_001269548 NM_001282620 NP_001269549 NM_002070 NP_002061
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17635935}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17635935}. Cell membrane {ECO:0000269|PubMed:17635935}. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody.
Top Pathways Circadian entrainment, Oxytocin signaling pathway, Estrogen signaling pathway, Adrenergic signaling in cardiomyocytes, Glutamatergic synapse

G α i-2 (L5) - sc-13534 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G<sub>α i-2</sub> (L-5): sc-13534. Western blot analysis of G<sub>α i-2</sub> expression in U-937 whole cell lysate.

G α i-2 (T-19) - sc-7276 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
G<sub>α i-2</sub> (T-19): sc-7276. Western blot analysis of G<sub>α i-2</sub> expression in U-937 whole cell lysate.

Anti-G protein alpha Inhibitor 2 antibody - ab154155 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-G protein alpha Inhibitor 2 antibody (ab154155) at 1/2000 dilution + Jurkat whole cell lysate at 30 µg

Anti-G protein alpha Inhibitor 2 antibody - ab20392 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lanes 1 & 3 : Anti-G protein alpha Inhibitor 2 antibody (ab20392) at 1/1000 dilutionLane 2 : No primaryLane 1 : Rat RH7777 whole cell lysateLane 2 : Rat RH7777 whole cell lysateLane 3 : Rat RH7777 whole cell lysateLysates/proteins at 15 µg per lane.SecondaryLane 1 : No secondaryLanes 2 - 3 : Alkaline phosphatase conjugated goat anti-rabbitPerformed under reducing conditions.

Anti-G protein alpha Inhibitor 2 antibody - ab118578 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with ab118578 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-G protein alpha Inhibitor 2 antibody - ab81452 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-G protein alpha Inhibitor 2 antibody (ab81452) at 1 µg/ml (in 5% skim milk / PBS buffer) + fetal lung lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-G protein alpha Inhibitor 2 antibody - ab81446 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-G protein alpha Inhibitor 2 antibody (ab81446) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal Brain Lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-G protein alpha Inhibitor 2 antibody - ab123427 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-G protein alpha Inhibitor 2 antibody (ab123427) at 1/100 dilution + SK-BR-3 cell line lysate at 35 µg

Anti-G protein alpha Inhibitor 2 antibody - ab55117 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-G protein alpha Inhibitor 2 antibody [EPR9468] - ab137050 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9468
All lanes : Anti-G protein alpha Inhibitor 2 antibody [EPR9468] (ab137050) at 1/1000 dilutionLane 1 : HL60 cell lysateLane 2 : U937 cell lysateLane 3 : MCF7 cell lysateLane 4 : HeLa cell lysateLane 5 : U-87 MG cell lysateLane 6 : C6 cell lysateLane 7 : RAW 264.7 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit IgG at 1/2000 dilution

Anti-G protein alpha Inhibitor 2 antibody [EPR9469] - ab157204 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9469
ab157204 showing +ve staining in Human normal liver.

Anti-GNAI2 Antibody (aa78-107, PE) - LS-C257832 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody (aa231-351) - LS-C23981 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody - LS-C23983 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GNAI2 Antibody - LS-C23984 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-GNAI2 Antibody - LS-C121847 from LifeSpan Bioscience

Prices $605.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody - LS-C152925 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GNAI2 Antibody (aa1-356, clone 10C405, Azide-free) - LS-C183660 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10C405

Anti-GNAI2 Antibody (aa78-107, APC) - LS-C257826 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody (aa78-107, AP) - LS-C257827 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody (aa78-107, Biotin) - LS-C257828 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody (aa78-107, Azide-free, HRP) - LS-C257830 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody (aa78-107, FITC) - LS-C257829 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAI2 Antibody (C-Terminus) - LS-C81893 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-GNAI2 Antibody (aa146-195) - LS-C81892 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.
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