POLR2L

Gene Symbol POLR2L
Entrez Gene 5441
Alt Symbol RBP10, RPABC5, RPB10, RPB10beta, RPB7.6, hRPB7.6
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Other Description DNA-directed RNA polymerase III subunit L|DNA-directed RNA polymerases I, II, and III subunit RPABC5|RNA polymerase II 7.6 kDa subunit|RNA polymerases I, II, and III subunit ABC5|RPB10 homolog
Swissprots P62875 Q6FHX3
Accessions CAA87657 CAA87658 EAX02408 P62875 AJ420546 AK311997 BAG34935 BC005903 AAH05903 BC018649 AAH18649 BQ435190 BU679804 CR536565 CAG38802 DQ893146 ABM84072 DQ896440 ABM87439 DQ896562 ABM87561 U37690 AAA91459 NM_021128 NP_066951
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16809778, ECO:0000269|PubMed:9852112}.
Top Pathways Huntington's disease, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase

POLR2L 293 Cell Lysate - 405990 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

POLR2L Overexpression Lysate (Native) - NBL1-14588 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: POLR2L Overexpression Lysate (Adult Normal) [NBL1-14588] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for POLR2L.

POLR2L Over-expression Lysate Product - GWB-588F77 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

POLR2L Overexpression Lysate (Denatured) - H00005441-T04 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human POLR2L Knockdown Stable Cell Line - CSC-DC012102 from Creative biogene

Category Cell Line
Species Human
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