MIF

Gene Symbol	MIF
Entrez Gene	4282
Alt Symbol	GIF, GLIF, MMIF
Species	Human
Gene Type	protein-coding
Description	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Other Description	L-dopachrome isomerase|L-dopachrome tautomerase|macrophage migration inhibitory factor|phenylpyruvate tautomerase
Swissprots	Q6FHV0 B2R4S3 A5Z1R8 P14174 Q2V4Y5
Accessions	AAA21814 ABB96245 EAW59620 P14174 AF469046 AAL78635 AK311929 BAG34870 BC000447 AAH00447 BC007376 BC007676 AAH07676 BC008914 AAH08914 BC013976 AAH13976 BC022414 AAH22414 BC051440 BC053376 AAH53376 BT007148 AAP35812 CR407644 CAG28572 CR456520 CAG30406 CR541651 CAG46452 CU013120 CAK54551 CU013408 CAK54850 DQ892195 ABM83121 DQ895390 ABM86316 JQ846015 AFM09726 L10612 AAA35892 M25639 AAA36315 M95775 AAA36179 Z23063 CAA80598 NM_002415 NP_002406
Function	Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. {ECO:0000269|PubMed:15908412, ECO:0000269|PubMed:17443469, ECO:0000269|PubMed:23776208}.
Subcellular Location	Secreted. Cytoplasm. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non- classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.
Top Pathways	Phenylalanine metabolism, Tyrosine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MIF Human ELISA Kit - ab100594 from Abcam Category ELISA Kit Prices $749.00 Sizes 1 x 96 tests Sensitivity < 6 pg/ml Range 8.23 pg/ml - 6000 pg/ml

Human MIF ELISA Kit (Sandwich ELISA) - LS-F2693 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 20 pg/ml Range 8.23-2000 pg/ml

Human MIF ELISA Kit (Sandwich ELISA) - LS-F4112 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.54 ng/ml Range 8.23-2000 pg/ml

Rat MIF ELISA Kit (Sandwich ELISA) - LS-F5437 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 8.23-2000 pg/ml

Mouse MIF ELISA Kit (Sandwich ELISA) - LS-F5436 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 31.25 pg/ml Range 8.23-2000 pg/ml

Human MIF ELISA Kit (Sandwich ELISA) - LS-F152 from LifeSpan Bioscience Category ELISA Kit Prices $510.00, $910.00, $2,100.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 8.23 pg/ml Range 8.23-2000 pg/ml

Human MIF ELISA Kit (Sandwich ELISA) - LS-F712 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 8.23-2000 pg/ml

Human MIF ELISA Kit (Sandwich ELISA) - LS-F12037 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 8.23-2000 pg/ml

Rat MIF ELISA Kit (Sandwich ELISA) - LS-F12036 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 8.23-2000 pg/ml

Human MIF ELISA Kit - RAB0360 from Sigma-Aldrich Category ELISA Kit Prices $485.50 Sizes 1 kt

Human MIF Quantikine ELISA Kit - DMF00B from R&D Systems Category ELISA Kit Prices $519.00, $2,491.00, $16,868.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 0.068 ng/mL Range 0.2 - 10 ng/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine, Human Milk)

Human MIF Quantikine PharmPak (50 Plates) - PDMF00B from R&D Systems Category ELISA Kit Sensitivity 0.068 ng/mL Range 0.156 - 10 ng/mL (Serum, Cell Culture Supernates, Human Milk, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine)

Human MIF Quantikine SixPak (6 Plates) - SMF00B from R&D Systems Category ELISA Kit Sensitivity 0.068 ng/mL Range 0.156 - 10 ng/mL (Serum, Cell Culture Supernates, Human Milk, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine)

Human MIF DuoSet ELISA - DY289 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Mouse MIF DuoSet ELISA - DY1978 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Quantikine Immunoassay Control Set 694 for Human MIF - QC122 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

MIF ELISA Kit (Human) : 96 Wells (OKAG00237) - OKAG00237 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 32 pg/mL Range 32-2,000 pg/mL

Macrophage MigRation Inhibitory Factor, Human, ELISA Kit - E01M0209 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 50-1000pg/ml

Macrophage Migration Inhibitory Factor, MIF, Human, ELISA Kit - E-EL-H1530 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

Macrophage Migration Inhibitory Factor, MIF, Mouse, ELISA Kit - E-EL-M0771 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Macrophage Migration Inhibitory Factor, MIF, Rat, ELISA Kit - E-EL-R0608 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Macrophage Migration Inhibitory Factor, MIF, Rabbit, ELISA Kit - E-EL-RB0644 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Macrophage Migration Inhibitory Factor, MIF, Chicken, ELISA Kit - E-EL-Ch0273 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Macrophage Migration Inhibitory Factor, MIF, Porcine, ELISA Kit - E-EL-P1327 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Macrophage Migration Inhibitory Factor, MIF, Guinea Pig, ELISA Kit - E-EL-GP0747 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Search more