RUNX1T1

Gene Symbol	RUNX1T1
Entrez Gene	862
Alt Symbol	AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Species	Human
Gene Type	protein-coding
Description	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Other Description	CBFA2T1 isoform r1t1-11a62|CBFA2T1 isoform r1t1-11a63|CBFA2T1 isoform r1t1-11a64|CBFA2T1 isoform r1t1-11a65|CBFA2T1 isoform r1t1-7a47|CBFA2T1 isoform r1t1-7a48|CBFA2T1 isoform r1t1-7a49|CBFA2T1 isoform r1t1-7a50|CBFA2T1 isoform r1t1-7a52|CBFA2T1 isoform r1t1-7d53|CBFA2T1 isoform r1t1-7d54|CBFA2T1 isoform r1t1-7d55|CBFA2T1 isoform r1t1-7d56|CBFA2T1 isoform r1t1-8a57|CBFA2T1 isoform r1t1-8a58|CBFA2T1 isoform r1t1-8a59|CBFA2T1 isoform r1t1-8a60|acute myelogenous leukemia 1 translocation 1, cyclin-D related|core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related|eight twenty one protein|myeloid translocation gene on 8q22|protein CBFA2T1|zinc finger MYND domain-containing protein 2
Swissprots	Q7Z4J5 E7EPN4 Q6IBL1 O14784 Q14873 Q9BRZ0 Q6NXH1 Q06455 B7Z4P4 Q16239 Q06456
Accessions	AAB32126 AAC28931 AAC28932 AAC28933 AAC28934 AAD14974 AAG33024 BAB88555 EAW91681 EAW91682 EAW91683 EAW91684 EAW91685 EAW91686 Q06455 AA506749 AF018283 AAC26143 AF131817 AK057707 AK297616 BAH12630 AK312592 BAG35486 AL049240 BC005850 AAH05850 BC067078 AAH67078 BC139783 BT009871 AAP88873 CR456792 CAG33073 D14289 BAA03247 D14821 BAA03558 D43638 BAA07755 DA499596 DA500281 DA503204 DA504975 DA770917 DA774453 DA776825 DA776968 DA777240 DA779230 DA787376 DA795825 DA796892 JF432279 ADZ15496 KF946505 AHK05721 KF946506 AHK05722 KF946507 AHK05723 KF946508 AHK05724 KF946509 AHK05725 KF946510 AHK05726 KF946511 AHK05727 KF946512 AHK05728 KF946513 AHK05729 KF946514 AHK05730 KF946515 AHK05731 KF946516 AHK05732 KF946517 AHK05733 KF946518 AHK05734 KF946519 AHK05735 KF946520 AHK05736 KF946521 AHK05737 KF946522 AHK05738 KF946523 AHK05739 S82690 AAB46751 X79990 CAA56311 Z35296 XM_006716676 XP_006716739 XM_011517351 XP_011515653 XM_011517352 XP_011515654 XM_011517353 XP_011515655 XR_928359 NM_001198625 NP_001185554 NM_001198626 NP_001185555 NM_001198627 NP_001185556 NM_001198628 NP_001185557 NM_001198629 NP_001185558 NM_001198630 NP_001185559 NM_001198631 NP_001185560 NM_001198632 NP_001185561 NM_001198633 NP_001185562 NM_001198634 NP_001185563 NM_001198679 NP_001185608 NM_004349 NP_004340 NM_175634 NP_783552 NM_175635 NP_783553 NM_175636 NP_783554
Function	Transcription regulator that excerts its function by binding to histone deacetylases and transcription factors. Can repress transactivation mediated by TCF12. {ECO:0000269|PubMed:10973986, ECO:0000269|PubMed:16803958}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00440, ECO:0000269|PubMed:10973986}. Note=Colocalizes with ATN1 in discrete nuclear dots.
Tissue Specificity	Most abundantly expressed in brain. Lower levels in lung, heart, testis and ovary.
Top Pathways	Acute myeloid leukemia, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RUNX1T1 / ETO protein fragment - ab152255 from Abcam Category Protein Source Wheat germ Species Human

Human RUNX1T1 / ETO protein fragment - ab152256 from Abcam Category Protein Source Wheat germ Species Human

RUNX1T1 / ETO Antibody Blocking Peptide - LS-E12027 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RUNX1T1 / ETO Antibody Blocking Peptide - LS-E21270 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RUNX1T1 / ETO Antibody Blocking Peptide - LS-E21271 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RUNX1T1/ETO Protein - H00000862-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RUNX1T1/ETO Partial Recombinant Protein - H00000862-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RUNX1T1 - H00000862-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RUNX1T1 - H00000862-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RUNX1T1 - H00000862-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RUNX1T1 - H00000862-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RUNX1T1 fusion protein - Ag7893 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RUNX1T1 fusion protein - Ag7892 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RUNX1T1, His-tagged - RUNX1T1-2472H from Creative Biomart Category Protein Source E.coli Species Human

RUNX1T1 (transcript variant 4) - TP300898 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RUNX1T1 (transcript variant 3) - TP322426 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MTG8, Peptide - MBS658180 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Species Human, Rodent

MTG8, Peptide - MBS659451 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Species Human, Rodent

RUNX1T1/ETO Recombinant Protein Antigen - NBP2-49644PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

RUNX1T1 Peptide, Human - M34GP13693H from Creative Peptides Category Peptide Source Synthetic. Species Human

RUNX1T1/ETO Recombinant Protein Antigen - NBP2-55747PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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