| Gene Symbol | Atp6v0d1 |
|---|---|
| Entrez Gene | 11972 |
| Alt Symbol | AI267038, Ac39, Atp6d, P39, VATX, Vma6 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal V0 subunit D1 |
| Other Description | ATPase, H+ transporting, V0 subunit D|ATPase, H+ transporting, lysosomal (vacuolar proton pump), 42 kDa|ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D|V-ATPase 40 kDa accessory protein|V-ATPase AC39 subunit|V-ATPase subunit d 1|V-type proton ATPase subunit d 1|lysosomal 38kDa|physophilin|vacuolar proton pump subunit d 1 |
| Swissprots | Q54A57 Q9QWJ2 P51863 |
| Accessions | EDL11286 P51863 AB088408 BAC57954 AK083372 BAC38889 AK133921 AK171515 BAE42500 AK213362 BC011075 AAH11075 U13840 AAC83085 U21549 AAA92288 NM_013477 NP_038505 |
| Function | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Localizes to centrosome and the base of the cilium. {ECO:0000250}. |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12527205, ECO:0000269|PubMed:12963731}. |
| Top Pathways | Phagosome, Rheumatoid arthritis, Collecting duct acid secretion, Synaptic vesicle cycle, Lysosome |
V-ATPase D1 CRISPR/Cas9 KO Plasmid (m) - sc-419255 from Santa Cruz Biotechnology
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V-ATPase D1 HDR Plasmid (m) - sc-419255-HDR from Santa Cruz Biotechnology
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V-ATPase D1 Double Nickase Plasmid (m) - sc-419255-NIC from Santa Cruz Biotechnology
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V-ATPase D1 Double Nickase Plasmid (m2) - sc-419255-NIC-2 from Santa Cruz Biotechnology
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V-ATPase D1 CRISPR Activation Plasmid (m) - sc-419255-ACT from Santa Cruz Biotechnology
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V-ATPase D1 CRISPR Activation Plasmid (m2) - sc-419255-ACT-2 from Santa Cruz Biotechnology
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V-ATPase D1 Lentiviral Activation Particles (m) - sc-419255-LAC from Santa Cruz Biotechnology
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V-ATPase D1 Lentiviral Activation Particles (m2) - sc-419255-LAC-2 from Santa Cruz Biotechnology
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V-ATPase D1 siRNA (m) - sc-63208 from Santa Cruz Biotechnology
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V-ATPase D1 shRNA Plasmid (m) - sc-63208-SH from Santa Cruz Biotechnology
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V-ATPase D1 shRNA (m) Lentiviral Particles - sc-63208-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN27229 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27229 from Sigma-Aldrich
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ATP6V0D1 siRNA (Mouse) - CRM0310 from Cohesion Biosciences
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ATP6V0D1 - MBS8207197 from MyBioSource
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shRNA set against Mouse ATP6V0D1 (NM_013477.3) - SHH243042 from Creative biogene
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shRNA set against Mouse Atp6v0d1(NM_013477.3) - SHG083449 from Creative biogene
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ATP6V0D1 shRNA Plasmid (Mouse) - CHM0310 from Cohesion Biosciences
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ATP6V0D1 miRNA 3'UTR clone - MiUTR1M-01827 from Creative biogene
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