Dnmt3l

Gene Symbol Dnmt3l
Entrez Gene 54427
Alt Symbol D6Ertd14e, ecat7
Species Mouse
Gene Type protein-coding
Description DNA (cytosine-5-)-methyltransferase 3-like
Other Description DNA (cytosine-5)-methyltransferase 3-like
Swissprots Q9CWR8
Accessions EDL31748 EDL31749 Q9CWR8 AF220524 AAF73868 AJ404467 CAB94726 AK010434 BAB26936 AV473569 AV511576 BC083147 AAH83147 EF051621 EF051622 EF051623 EF051624 ABN46989 XM_011243514 XP_011241816 NM_001081695 NP_001075164 NM_001284197 NP_001271126 NM_001284198 NP_001271127 NM_001284199 NP_001271128 NM_001284200 NP_001271129 NM_019448 NP_062321
Function Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. {ECO:0000269|PubMed:11719692, ECO:0000269|PubMed:15671018}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in testis, thymus, ovary, and heart.

SignalSilence ® DNMT3L siRNA II (Mouse Specific) - 12308 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from F9 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® DNMT3L siRNA I (Mouse Specific) #12307 (+), or SignalSilence ® DNMT3L siRNA II (Mouse Specific) (+), using DNMT3L Antibody (Mouse Specific) #12309 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The DNMT3L Antibody (Mouse Specific) confirms silencing of DNMT3L expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

SignalSilence ® DNMT3L siRNA I (Mouse Specific) - 12307 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from F9 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® DNMT3L siRNA I (Mouse Specific) (+), or SignalSilence ® DNMT3L siRNA II (Mouse Specific) #12308 (+), using DNMT3L Antibody (Mouse Specific) #12309 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The DNMT3L Antibody (Mouse Specific) confirms silencing of DNMT3L expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

Dnmt3L CRISPR/Cas9 KO Plasmid (m) - sc-424871 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L HDR Plasmid (m) - sc-424871-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L Double Nickase Plasmid (m) - sc-424871-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L Double Nickase Plasmid (m2) - sc-424871-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L CRISPR Activation Plasmid (m) - sc-424871-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L CRISPR Activation Plasmid (m2) - sc-424871-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L Lentiviral Activation Particles (m) - sc-424871-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L Lentiviral Activation Particles (m2) - sc-424871-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Dnmt3L siRNA (m) - sc-37762 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Dnmt3L shRNA Plasmid (m) - sc-37762-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Dnmt3L shRNA (m) Lentiviral Particles - sc-37762-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU022701 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN30149 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30149 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DNMT3L siRNA (Mouse) - CRM5524 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

DNMT3L - MBS8202980 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse DNMT3L (NM_019448.3) - SHH280041 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Dnmt3l(NM_019448.3) - SHH012701 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Dnmt3l(NM_001081695.1) - SHH012737 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse DNMT3L siRNA - orb285000 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

DNMT3L shRNA Plasmid (Mouse) - CHM5524 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

DNMT3L miRNA 3'UTR clone - MiUTR1M-03944 from Creative biogene

Species Reactivities Mouse

DNMT3L miRNA 3'UTR clone - MiUTR1M-03945 from Creative biogene

Species Reactivities Mouse
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