| Gene Symbol |
HSD17B1
|
| Entrez Gene |
3292
|
| Alt Symbol |
EDH17B2, EDHB17, HSD17, SDR28C1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hydroxysteroid (17-beta) dehydrogenase 1
|
| Other Description |
17-beta-HSD 1|17-beta-hydroxysteroid dehydrogenase type 1|20 alpha-hydroxysteroid dehydrogenase|20-alpha-HSD|E2DH|estradiol 17-beta-dehydrogenase 1|estradiol 17-beta-dehydrogenase-1|hydroxysteroid (17-beta) dehydrogenase 1 isoform|placental 17-beta-hydroxysteroid dehydrogenase|short chain dehydrogenase/reductase family 28C member 1|short chain dehydrogenase/reductase family 28CE, member 1
|
| Swissprots |
B3KXS1 Q2M2L8 P14061
|
| Accessions |
AAB16941 AAB16942 AAB17014 AAD05019 EAW60836 P14061 AK127832 BAG54583 AK300143 BAG61929 AK300159 BAG61942 AK300452 BAG62173 AK316292 BAH14663 BC019592 BC033110 AAH33110 BC037415 BC104752 AAI04753 BC111935 AAI11936 BF112114 BQ575124 DQ469954 ABF13478 M36263 AAA35600 X13440 CAA31792 XM_005257292 XP_005257349 XM_006721857 XP_006721920 XM_006721858 XP_006721921 XM_006721859 XP_006721922 XM_011524729 XP_011523031 XM_011524730 XP_011523032 XM_011524731 XP_011523033 XM_011524732 XP_011523034 XR_934451 NM_000413 NP_000404
|
| Function |
Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Steroid hormone biosynthesis, Ovarian steroidogenesis
|