Gene Symbol |
St6gal1
|
Entrez Gene |
25197
|
Alt Symbol |
Siat1
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
|
Other Description |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1|ST6Gal I|ST6GalI|Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase)|Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase)|alpha 2,6-ST 1|beta galactoside alpha 2,6 sialyltransferase 1|beta-galactoside alpha-2,6-sialyltransferase 1
|
Swissprots |
P13721
|
Accessions |
EDL78084 EDL78085 P13721 BF418553 FQ210708 FQ222565 FQ224146 M18769 AAA41196 M73987 AAB06269 M83143 AAB07233 XM_006248501 XP_006248563 XM_008768792 XP_008767014 NM_001113344 NP_001106815 NM_147205 NP_671738
|
Function |
Transfers sialic acid from CMP-sialic acid to galactose- containing acceptor substrates. {ECO:0000269|PubMed:3121604}.
|
Subcellular Location |
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid.
|
Tissue Specificity |
Strongly expressed in liver, spleen, lung, kidney and submaxillary gland and weakly in heart and brain.
|
Top Pathways |
N-Glycan biosynthesis, Other types of O-glycan biosynthesis
|