| Gene Symbol |
GSTA3
|
| Entrez Gene |
2940
|
| Alt Symbol |
GSTA3-3, GTA3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutathione S-transferase alpha 3
|
| Other Description |
GST class-alpha member 3|S-(hydroxyalkyl)glutathione lyase A3|glutathione S-alkyltransferase A3|glutathione S-aralkyltransferase A3|glutathione S-aryltransferase A3|glutathione S-transferase A3|glutathione S-transferase A3-3
|
| Swissprots |
Q9H415 Q16772 Q068V6 Q8WWA8 O43468
|
| Accessions |
AAA74634 ABI75350 EAX04390 EAX04391 Q16772 AA846513 AF020919 AAD04712 AF508266 AAM33360 AI199811 BC020619 AAH20619 BG573805 DQ891389 ABM82315 DQ894564 ABM85490 DT932587 XM_006715072 XP_006715135 XM_011514533 XP_011512835 XR_926166 XR_926167 NM_000847 NP_000838
|
| Function |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)- pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. {ECO:0000269|PubMed:15595823, ECO:0000269|PubMed:20083122}.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
|
