| Gene Symbol | Mmp12 |
|---|---|
| Entrez Gene | 17381 |
| Alt Symbol | AV378681, Mmel |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | matrix metallopeptidase 12 |
| Other Description | MME|MMP-12|macrophage elastase|macrophage metalloelastase|macrophage-metalloelastase|matrix metalloproteinase 12|matrix metalloproteinase-12 |
| Swissprots | Q4FJM7 Q8BJB9 Q8BJ92 Q8BJB8 Q3TBV6 Q8VED6 Q3U1S8 Q3TD61 Q8BJB6 Q3TB28 Q3UBC5 P34960 Q3U2R8 Q8BJB3 Q3U1S9 Q3TBV9 |
| Accessions | EDL24933 P34960 AK089295 BAC40832 AK089309 BAC40836 AK089335 BAC40846 AK089452 BAC40889 AK089509 BAC40909 AK089523 BAC40913 AK090051 BAC41067 AK150596 BAE29689 AK151021 BAE30039 AK151273 BAE30260 AK151933 BAE30809 AK155139 BAE33072 AK155743 BAE33411 AK155747 BAE33414 AK155748 BAE33415 AK155841 AK155865 BAE33469 AK170360 BAE41743 AK170364 BAE41746 AK170500 BAE41839 AK170667 AK170798 BAE42035 AK170804 BAE42039 AK170976 BAE42154 AK171006 BAE42177 AK171032 BAE42198 AK171036 BAE42201 AK171176 BAE42294 AK171428 BAE42446 AK171435 AK171447 BAE42457 AK171448 BAE42458 AK171449 BAE42459 AK171450 BAE42460 AK171466 BAE42472 AK171468 BAE42474 AK171470 BAE42476 AK171472 BAE42478 AK171485 BAE42486 AK171518 BAE42502 AK171542 BAE42516 AK171570 BAE42531 AY622972 AAT46403 BC019135 AAH19135 CT010377 CAJ18584 M82831 AAA39526 XM_011242357 XP_011240659 XM_011242358 XP_011240660 NM_008605 NP_032631 |
| Function | May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |