| Gene Symbol |
Nr1i3
|
| Entrez Gene |
65035
|
| Alt Symbol |
CAR
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
nuclear receptor subfamily 1, group I, member 3
|
| Other Description |
constitutive androstane receptor|nuclear receptor constitutive active receptor|nuclear receptor subfamily 1 group I member 3|strain Fischer nuclear receptor (CAR)
|
| Swissprots |
Q9QUS1
|
| Accessions |
BAC84955 EDL94605 EDL94606 EDL94607 Q9QUS1 AB104736 BAC82431 AB105072 BAC84956 AB204897 BAE19955 AB204898 BAE19956 AB204899 BAE19957 AB204900 BAE19958 AF133094 AAF22566 AF133095 AAF22567 AF233431 AAF37700 BC089763 AAH89763 XM_006250261 XP_006250323 XM_008769758 XP_008767980 XM_008769759 XP_008767981 NM_001270838 NP_001257767 NM_001270839 NP_001257768 NM_001270840 NP_001257769 NM_022941 NP_075230
|
| Function |
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}. Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Recruited to the cytoplasm by DNAJC7. {ECO:0000250}.
|