CR2

Gene Symbol CR2
Entrez Gene 1380
Alt Symbol C3DR, CD21, CR, CVID7, SLEB9
Species Human
Gene Type protein-coding
Description complement component (3d/Epstein Barr virus) receptor 2
Other Description EBV receptor|complement C3d receptor|complement receptor type 2
Swissprots Q5SR46 C9JHD2 Q14212 Q53EL2 Q5BKT9 P20023 Q13866 Q5SR48
Accessions AAB04638 AAG37227 ABK41929 CAA66910 EAW93481 EAW93482 EAW93483 P20023 AI765035 AK223627 BAD97347 AK301496 BAG63007 AU133057 AW303499 BC032548 BC090937 AAH90937 BC136394 AAI36395 BQ004295 J03565 AAA35784 M26004 AAA35786 M26317 S62696 AAB27186 X68990 CAA48779 Y00649 CAA68674 XM_011509206 XP_011507508 NM_001006658 NP_001006659 NM_001877 NP_001868
Function Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. {ECO:0000269|PubMed:7753047}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
Top Pathways Complement and coagulation cascades, Hematopoietic cell lineage, B cell receptor signaling pathway, Epstein-Barr virus infection

CD21 (A-3) - sc-13135 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD21 (A-3): sc-13135. Immunoperoxidase staining of formalin-fixed, paraffin-embedded normal human tonsil tissue showing membrane staining.

CD21 (HB-5) - sc-18857 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD21 (HB-5): sc-18857. Western blot analysis of CD21 expression in Raji whole cell lysate under non-reducing conditions.

CD21 (H-240) - sc-9151 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CD21 (C-20) - sc-7025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD21 (C-20): sc-7025. Western blot analysis of CD21 expression in Daudi whole cell lysate.

CD21 (BU32) - sc-52464 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

CD21 (B-ly4) - sc-51724 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD21 (B-ly4): sc-51724. Indirect FCM analysis of human peripheral blood leukocytes stained with CD21 (B-ly4), followed by PE-conjugated goat anti-mouse IgG<sub>1</sub>: sc-3764. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

Anti-CD21 antibody - ab190391 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of CD21 in Immunoprecipitates of Ramos whole cell lysates (1 mg for IP, 20% of IP loaded) using ab190391 at 6 µg/reaction for IP and 1µg/ml for WB detection (Lane 1). Lane 2 represents control IgG IP. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-CD21 antibody [1F8] - ab9492 from Abcam

Prices $376.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone 1F8
ab9492 staining human tonsil by IHC-P

Anti-CD21 antibody [1F8], prediluted - ab7290 from Abcam

Prices $370.00
Sizes 6 ml
Host Mouse
Clonality Monoclonal
Clone 1F8

Anti-CD21 antibody [B-D6] - ab46903 from Abcam

Prices $370.00
Sizes 2.5 ml
Host Mouse
Clonality Monoclonal
Clone B-D6

Anti-CD21 antibody [B-E5] - ab46900 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-E5
A typical lymphocytes staining pattern with ab46900.

Anti-CD21 antibody [B-E5] - ab46897 from Abcam

Prices $370.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-E5

Anti-CD21 antibody [B-E5] (FITC) - ab46901 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone B-E5
A typical lymphocytes staining pattern with ab46901.

Anti-CD21 antibody [B-E5] (Phycoerythrin) - ab46902 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone B-E5
A typical staining pattern with ab46902.

Anti-CD21 antibody [Bu32] - ab54253 from Abcam

Prices $379.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone Bu32
Human peripheral blood lymphocytes stained with ab54253 (red line). Human whole blood was processed using a modified protocol based on Chow et al, 2005 (PMID: 16080188). In brief, human whole blood was fixed in 4% formaldehyde (methanol-free) for 10 min at 22°C. Red blood cells were then lyzed by the addition of Triton X-100 (final concentration - 0.1%) for 15 min at 37°C. For experimentation, cells were treated with 50% methanol (-20°C) for 15 min at 4°C. Cells were then incubated with the antibody (ab54253, 0.1μg/1x106 cells) for 30 min at 4°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 4°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >30,000 total events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. Gating strategy - peripher

Anti-CD21 antibody [BU32] (FITC) - ab187837 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone BU32

Anti-CD21 antibody [BU36] - ab952 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone BU36

Anti-CD21 antibody [EP3093] - ab75985 from Abcam

Prices $388.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP3093
All lanes : Anti-CD21 antibody [EP3093] (ab75985) at 1/2000 dilutionLane 1 : Daudi cell lysateLane 2 : Raji cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CD21 antibody [EP3093] (DyLight® 488) - ab139873 from Abcam

Prices $337.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP3093
Flow cytometric analysis of Daudi cells labelling CD21 with ab139873 at 1/100 dilution (red) compared to a nonspecific control antibody (green).

Anti-CD21 antibody [HI21a] (Allophycocyanin) - ab91158 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI21a
ab91158 at 20µl/106 cell staining CD21 in normal Human peripheral blood by Flow Cytometry.

Anti-CD21 antibody [HI21a], prediluted (CF405M) - ab123615 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI21a
ab123615, at 5 µl/106 cells, staining CD21 in normal Human peripheral blood cells by Flow Cytometry. Cells in the lymphocyte gate were used for analysis.

Anti-CD21 antibody [LT21] - ab1090 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone LT21
Double staining of CD21 and CD79a in human, canine and porcine B lymphocytes using ab1090 and ab76908 by Flow Cytometery.

Anti-CD21 antibody [LT21] (Alexa Fluor® 647) - ab187583 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone LT21

Anti-CD21 antibody [LT21] (FITC) - ab65809 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone LT21

Anti-CD21 antibody [LT21] (PE/Cy5®) - ab201303 from Abcam

Prices $359.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone LT21
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