FOXA3

Gene Symbol	FOXA3
Entrez Gene	3171
Alt Symbol	FKHH3, HNF3G, TCF3G
Species	Human
Gene Type	protein-coding
Description	forkhead box A3
Other Description	HNF-3-gamma|HNF-3G|TCF-3G|fork head-related protein FKH H3|forkhead box protein A3|hepatocyte nuclear factor 3, gamma|hepatocyte nuclear factor 3-gamma|transcription factor 3G
Swissprots	A9LYI5 P55318 Q53F16 Q9UMW9
Accessions	AAD51980 ABX44664 EAW57394 EAW57395 P55318 AK223473 BAD97193 BC016024 AAH16024 BT006720 AAP35366 L12141 AAA58477 NM_004497 NP_004488
Function	Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis. {ECO:0000250, ECO:0000269|PubMed:12695546}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089, ECO:0000269|PubMed:19706729}.
Tissue Specificity	Expressed in erythroleukemia and hepatoma cell lines and in liver and pancreas. Not expressed in any other cell lines or tissues examined. {ECO:0000269|PubMed:8499623}.
Top Pathways	Maturity onset diabetes of the young

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FOXA3 full length protein - ab134839 from Abcam Category Protein Source E. coli Species Human

FOXA3 Antibody Blocking Peptide - LS-E13223 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FOXA3 Antibody Blocking Peptide - LS-E11150 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FOXA3 Recombinant Protein - H00003171-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human FOXA3 Protein - H00003171-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FOXA3 / HNF3G - H00003171-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FOXA3 / HNF3G - H00003171-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FOXA3 / HNF3G - H00003171-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FOXA3 / HNF3G - H00003171-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FOXA3 fusion protein - ag14113 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

FOXA3 fusion protein - Ag14503 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Hepatocyte nuclear factor 3-gamma(FOXA3) - CSB-YP008796HU CSB-EP008796HU CSB-BP008796HU CSB-MP008796HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FOXA3, Peptide - MBS659473 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Species Human, Rodent

FOXA3, Peptide - MBS658233 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Species Human, Rodent

FOXA3-Antibody-C-term-Blocking-Peptide - BP6946b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FOXA3 Peptide, Human - M34GP05837H from Creative Peptides Category Peptide Source Synthetic. Species Human

Hepatocyte nuclear factor 3-gamma (FOXA3), Recombinant Protein - MBS962976 from MyBioSource Category Protein Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,765.00, $1,765.00, $2,230.00, $2,230.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

FOXA3 Recombinant Protein Antigen - NBP2-55686PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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