AHR

Gene Symbol AHR
Entrez Gene 196
Alt Symbol bHLHe76
Species Human
Gene Type protein-coding
Description aryl hydrocarbon receptor
Other Description AH-receptor|ah receptor|aromatic hydrocarbon receptor|class E basic helix-loop-helix protein 76
Swissprots Q13803 Q13728 A4D130 Q13804 P35869
Accessions AAA92082 AAA92083 AAA92084 BAA07235 CCO13674 EAL24281 EAW93686 EAW93687 P35869 AA329775 AK130815 AK307495 BC021696 BC069390 AAH69390 BC070080 AAH70080 BQ020427 BQ024331 BX505160 D16354 BAA03857 L19872 AAA16210 NM_001621 NP_001612
Function Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. {ECO:0000269|PubMed:10395741, ECO:0000269|PubMed:7961644}.
Subcellular Location Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
Tissue Specificity Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. {ECO:0000269|PubMed:7515333, ECO:0000269|PubMed:8246913}.

Ah Receptor CRISPR/Cas9 KO Plasmid (h) - sc-400297 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor HDR Plasmid (h) - sc-400297-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor Double Nickase Plasmid (h) - sc-400297-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor Double Nickase Plasmid (h2) - sc-400297-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor CRISPR Activation Plasmid (h) - sc-400297-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor CRISPR Activation Plasmid (h2) - sc-400297-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor Lentiviral Activation Particles (h) - sc-400297-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor Lentiviral Activation Particles (h2) - sc-400297-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ah Receptor siRNA (h) - sc-29654 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ah Receptor shRNA Plasmid (h) - sc-29654-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ah Receptor shRNA (h) Lentiviral Particles - sc-29654-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AHR RNAi - H00000196-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: AHR RNAi [H00000196-R01V] - Analysis of AHR over-expressed 293 cell line. Lane 2 cotransfected with AHR Validated Chimera RNAi. Lane 1 non-transfected control. Blot probed H00000196-M02. GAPDH ( 36.1 kDa ) used as loading control.

AHR RNAi - H00000196-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU039071 from Sigma-Aldrich

Category siRNA

AHR siRNA (Human) - CRH0136 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AHR - MBS8204599 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AHR (NM_001621.4) - SHH233694 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AHR(NM_001621.4) - SHG047203 from Creative biogene

Category siRNA
Species Reactivities Human

AHR shRNA Plasmid (Human) - CHH0136 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AHR miRNA 3'UTR clone - MiUTR1H-00252 from Creative biogene

Species Reactivities Human
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