| Gene Symbol |
DSG1
|
| Entrez Gene |
1828
|
| Alt Symbol |
CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
desmoglein 1
|
| Other Description |
cadherin family member 4|desmoglein-1|desmosomal glycoprotein 1|pemphigus foliaceus antigen
|
| Swissprots |
B7Z845 Q02413
|
| Accessions |
CAA04949 EAX01254 Q02413 AF088042 AF097935 AAC83817 AK302888 BAH13831 BC148374 AAI48375 BC153001 AAI53002 BX476267 CU456411 X56654 CAA39976 NM_001942 NP_001933
|
| Function |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, desmosome.
|
| Tissue Specificity |
Epidermis, tongue, tonsil and esophagus.
|
| Top Pathways |
Staphylococcus aureus infection
|