AFP

Gene Symbol AFP
Entrez Gene 174
Alt Symbol AFPD, FETA, HPAFP
Species Human
Gene Type protein-coding
Description alpha-fetoprotein
Other Description alpha-1-fetoprotein|alpha-fetoglobulin
Swissprots P02771 B2RBU3
Accessions AAA51674 AAA51675 AAB58754 CAA79592 EAX05681 P02771 AF484525 AF484526 AI336986 AK297669 BAG60031 AK297674 BAG60036 AK314817 BAG37340 BC027881 AAH27881 DQ890942 ABM81868 DQ894103 ABM85029 V01514 CAA24758 XM_011531704 XP_011530006 NM_001134 NP_001125
Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Subcellular Location Secreted.
Tissue Specificity Plasma. Synthesized by the fetal liver and yolk sac.
Top Pathways Hippo signaling pathway

AFP (3H8) Mouse mAb (Alexa Fluor ® 647 Conjugate) - 7765 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone 3H8
Confocal immunofluorescent analysis of Hep G2 (left) and HeLa (right) cells using AFP (3H8) Mouse mAb (Alexa Fluor® 647 Conjugate) (red). Actin filaments were labeled with Alexa Fluor® 488 phalloidin. Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

AFP (3H8) Mouse mAb (Alexa Fluor ® 488 Conjugate) - 7741 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone 3H8
Confocal immunofluorescent analysis of Hep G2 (left) and HeLa (right) cells using AFP (3H8) Mouse mAb (Alexa Fluor® 488 Conjugate) (green). Actin filaments were labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

AFP (3H8) Mouse mAb (Alexa Fluor ® 594 Conjugate) - 7877 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone 3H8
Confocal immunofluorescent analysis of Hep G2 (left) and HeLa (right) cells using AFP (3H8) Mouse mAb (Alexa Fluor® 594 Conjugate) (red). Actin filaments were labeled with Alexa Fluor® 488 phalloidin (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

AFP (3H8) Mouse mAb (Alexa Fluor ® 555 Conjugate) - 7800 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone 3H8
Confocal immunofluorescent analysis of Hep G2 (left) or HeLa (right) cells using AFP (3H8) Mouse mAb (Alexa Fluor® 555 Conjugate) (red). Actin filaments were labeled with Alexa Fluor® 488 phalloidin (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

AFP Antibody - 2137 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of recombinant AFP, using AFP Antibody.

AFP (3H8) Mouse mAb - 3903 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 3H8
Western blot analysis of extracts of various cell lines using AFP (3H8) Mouse mAb.

AFP (D12C1) Rabbit mAb - 4448 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D12C1
Western blot analysis of extracts from Hep G2 cells using AFP (D12C1) Rabbit mAb.

AFP (C-19) - sc-8108 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AFP (C-19): sc-8108. Western blot analysis of human recombinant AFP fusion protein.

AFP (H-9) - sc-166335 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AFP (H-9): sc-166335. Western blot analysis of AFP expression in non-transfected: sc-117752 (A) and human AFP transfected: sc-114125 (B) 293T whole cell lysates.

AFP (AFP05) - sc-69857 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AFP (AFP05): sc-69857. Western blot analysis of human recombinant AFP.

AFP (C3) - sc-8399 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AFP (C3): sc-8399. Western blot analysis of human purified alpha fetoprotein.

AFP (E-7) - sc-166450 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AFP (E-7): sc-166450. Western blot analysis of AFP expression in Hep G2 whole cell lysate.

AFP (F-8) - sc-166325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AFP (F-8): sc-166325. Western blot analysis of AFP expression in non-transfected: sc-117752 (A) and human AFP transfected: sc-114125 (B) 293T whole cell lysates.

AFP (H-140) - sc-15375 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AFP (H-140): sc-15375. Western blot analysis of human recombinant AFP.

AFP (39) - sc-130302 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AFP (39): sc-130302. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human stomach tissue showing cytoplasmic localization.

AFP (AFP-11) - sc-51506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
AFP (AFP-11): sc-51506. Western blot analysis of human recombinant AFP under non-reducing (A) and reducing (B) conditions.

AFP (1B10) - sc-80464 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
AFP (1B10): sc-80464. Western blot analysis of AFP expression in non-transfected 293T: sc-117752 (A), human AFP transfected 293T: sc-114125 (B) and Hep G2 (C) whole cell lysates.

Anti-alpha 1 Fetoprotein antibody - ab46799 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab46799 staining alpha 1 Fetoprotein in cat liver tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 2.5% serum for 30 minutes at 25°C; antigen retrieval was by heat mediation in 10mM citrate buffer, pH 6.0. Samples were incubated with primary antibody (1/50 in PBS + 1X casein) for 1 hour at 25°C. An undiluted HRP-conjugated horse anti-rabbit IgG polyclonal was used as the secondary antibody.See Abreview

Anti-alpha 1 Fetoprotein antibody - ab54745 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
alpha 1 Fetoprotein antibody (ab54745) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.

Anti-alpha 1 Fetoprotein antibody - ab182645 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling Alpha 1 fetoprotein with ab182645 at 1/60 dilution (left).  On the right is treated with the immunogen.

Anti-alpha 1 Fetoprotein antibody - ab115133 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-alpha 1 Fetoprotein antibody (ab115133) at 1 µg/ml + Liver (Human) Tissue Lysate - fetal normal tissue (ab29890) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-alpha 1 Fetoprotein antibody - ab116016 from Abcam

Prices $370.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-alpha 1 Fetoprotein antibody - ab31130 from Abcam

Host Duck
Clonality Polyclonal

Anti-alpha 1 Fetoprotein antibody - ab9372 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-alpha 1 Fetoprotein antibody - ab190874 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-alpha 1 Fetoprotein antibody (ab190874) at 0.3 µg/ml + HepG2 cell lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique
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