PSMB5

Gene Symbol PSMB5
Entrez Gene 5693
Alt Symbol LMPX, MB1, X
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) subunit, beta type, 5
Other Description PSX large multifunctional protease X|macropain epsilon chain|multicatalytic endopeptidase complex epsilon chain|proteasome beta 5 subunit|proteasome catalytic subunit 3|proteasome chain 6|proteasome epsilon chain|proteasome subunit MB1|proteasome subunit X|proteasome subunit beta type-5|proteasome subunit, beta type, 5
Swissprots Q86T01 Q9TNN9 B2R4N9 Q16242 P28074 B4DUM9 E9PAV2 Q6PEW2 Q7Z3B5 D3DS43
Accessions CAA64838 EAW66193 EAW66194 EAW66195 P28074 AK225888 AK300714 BAG62391 AK311895 BAG34836 BC057840 AAH57840 BC107720 AAI07721 BT006777 AAP35423 BU539357 BU632351 BX248299 CAD62626 BX538001 CAD97956 CD048996 HQ448536 ADQ33015 S74378 AAB33092 XM_005267871 XP_005267928 NM_001130725 NP_001124197 NM_001144932 NP_001138404 NM_002797 NP_002788
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage through the Nrf2-ARE pathway (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Proteasome

PSMB5-Over-expression-Lysate - LY10555a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag PSMB5 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PSMB5 gene (Lane 2, Cat. #LY10555a).

PSMB5 293T Cell Transient Overexpression Lysate(Denatured) - H00005693-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

PSMB5 293T Cell Transient Overexpression Lysate(Denatured) - H00005693-T02 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

PSMB5 overexpression lysate - LY400989 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

PSMB5 overexpression lysate - LY427268 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

PSMB5 293 Cell Lysate - 400928 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

PSMB5 Overexpression Lysate (Denatured) - H00005693-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: PSMB5 transfected lysate (29.04 KDa). Lane 2: Non-transfected lysate.

PSMB5 Overexpression Lysate (Native) - NBL1-14880 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: PSMB5 Overexpression Lysate (Adult Normal) [NBL1-14880] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PSMB5.

PSMB5 Over-expression Lysate Product - GWB-29F47B from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

PSMB5 Overexpression Lysate (Denatured) - H00005693-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

PSMB5 Overexpression Lysate (Denatured) - H00005693-T04 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

PSMB5 Overexpression Lysate (Denatured) - H00005693-T03 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human PSMB5 Knockdown Stable Cell Line - CSC-DC012590 from Creative biogene

Category Cell Line
Species Human
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