| Gene Symbol | Serpinb6a |
|---|---|
| Entrez Gene | 20719 |
| Alt Symbol | 4930482L21Rik, D330015H01Rik, PI-6, Serpinb6, Spi3, ovalbumin |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | serine (or cysteine) peptidase inhibitor, clade B, member 6a |
| Other Description | placental thrombin inhibitor|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6|serine (or cysteine) proteinase inhibitor, clade B, member 6a|serine protease inhibitor 3|serpin B6 |
| Swissprots | Q60854 |
| Accessions | EDL40870 EDL40871 EDL40872 Q60854 AK015611 AK033731 BAC28452 AK046950 AK084564 AK154700 BAE32772 AK167295 BAE39400 AK169145 BAE40924 AK183101 AK211615 BC006766 AAH06766 BC057950 AAH57950 CF732441 CT010346 CAJ18554 U25844 AAA79684 XM_006516623 XP_006516686 XM_011244299 XP_011242601 XM_011244300 XP_011242602 XM_011244301 XP_011242603 NM_001164117 NP_001157589 NM_001164118 NP_001157590 NM_001243192 NP_001230121 NM_009254 NP_033280 |
| Function | Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress. May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. {ECO:0000269|PubMed:17761692}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17761692, ECO:0000269|PubMed:20451170}. |
| Tissue Specificity | Expressed in the inner ear hair cells, keratinocytes of hair follicles and epidermis in abdominal skin. {ECO:0000269|PubMed:17761692, ECO:0000269|PubMed:20451170}. |
| Top Pathways | Amoebiasis |