| Gene Symbol |
ENTPD6
|
| Entrez Gene |
955
|
| Alt Symbol |
CD39L2, IL-6SAG, IL6ST2, NTPDase-6, dJ738P15.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
|
| Other Description |
CD39 antigen-like 2|CD39-like 2|HCV-E2 binding protein 1|NTPDase 6|ectonucleoside triphosphate diphosphohydrolase 6|ectonucleoside triphosphate diphosphohydrolase 6 (putative function)|interleukin 6 signal transducer-2
|
| Swissprots |
Q9UJD1 Q8N3H3 A6NCX6 D3DW49 O75354 Q5QPJ5 Q5QPJ2 Q7Z5B5 Q8TAS7
|
| Accessions |
EAX10095 EAX10096 EAX10097 EAX10098 EAX10099 O75354 AF039916 AAC39883 AF058296 AAC14279 AK074691 AK094030 AK095708 AK124625 AK128412 AK293256 BAG56788 AK295242 BAG58234 AK297954 BAG60268 AK300028 BAG61839 AK300514 BAG62226 AK302395 BAG63709 AK303786 BAG64743 AK308626 AL834158 CAD38864 AM393565 CAL38442 AY327581 AAP92131 AY459290 AAR23235 BC025980 AAH25980 CR936750 CR936765 DQ893396 ABM84322 EU176756 ABW03557 XM_005260878 XP_005260935 XM_005260881 XP_005260938 XM_005260882 XP_005260939 XM_005260883 XP_005260940 XM_005260884 XP_005260941 XM_005260885 XP_005260942 XM_005260886 XP_005260943 XM_005260887 XP_005260944 XM_006723665 XP_006723728 XM_011529396 XP_011527698 XM_011529397 XP_011527699 XM_011529398 XP_011527700 XM_011529399 XP_011527701 XM_011529400 XP_011527702 XM_011529401 XP_011527703 XR_937178 NM_001114089 NP_001107561 NM_001247 NP_001238
|
| Function |
Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5'-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Note=But also occurs in a soluble extracellular form.
|
| Tissue Specificity |
Expressed in most tissues, but predominantly in heart. {ECO:0000269|PubMed:11041856}.
|
| Top Pathways |
Purine metabolism, Pyrimidine metabolism
|