| Gene Symbol |
Kcnq3
|
| Entrez Gene |
29682
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, voltage-gated KQT-like subfamily Q, member 3
|
| Other Description |
KQT-like 3|potassium channel subunit alpha KvLQT3|potassium voltage-gated channel subfamily KQT member 3|potassium voltage-gated channel, KQT-like subfamily, member 3|potassium voltage-gated channel, subfamily Q, member 3|voltage-gated potassium channel subunit Kv7.3
|
| Swissprots |
O88944 Q9Z240
|
| Accessions |
EDM16162 EDM16163 EDM16164 O88944 AF091247 AAC79846 CB556681 CB741837 XM_008765495 XP_008763717 NM_031597 NP_113785
|
| Function |
Probably important in the regulation of neuronal excitability. Associates with KCNQ2 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in brain and sympathetic ganglia. In brain, expressed in cortex, hippocampus and at much lower levels in cerebellum. In sympathetic ganglia, expressed at approximately equal levels in both superior cervical ganglia and prevertebral ganglia.
|