FKBP6

Gene Symbol	FKBP6
Entrez Gene	8468
Alt Symbol	FKBP36
Species	Human
Gene Type	protein-coding
Description	FK506 binding protein 6, 36kDa
Other Description	36 kDa FKBP|PPIase FKBP6|immunophilin FKBP36|inactive PPIase FKBP6|inactive peptidyl-prolyl cis-trans isomerase FKBP6|peptidyl-prolyl cis-trans isomerase FKBP6|rotamase
Swissprots	Q9UDS0 O75344 B4DXT7 Q7Z4T4 G3V0I2
Accessions	CBH19283 EAW69684 EAW69685 EAW69686 O75344 AA909474 AF038847 AAC64249 AF447060 AAP97324 AK302121 BAG63499 AK310255 BC036817 AAH36817 BI461016 DB033483 DB450796 DB525126 EU176233 ABW03684 EU176537 ABW03338 GQ129339 ACT64473 GQ129340 ACT64474 XM_005250643 XP_005250700 XM_006716152 XP_006716215 XM_006716153 XP_006716216 XM_011516644 XP_011514946 NM_001135211 NP_001128683 NM_001281304 NP_001268233 NM_003602 NP_003593
Function	Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Does not localize to pi-bodies. Localizes to meiotic chromosome cores and regions of homologous chromosome synapsis (By similarity). {ECO:0000250}.
Tissue Specificity	Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FKBP6 (N-16) - sc-104249 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FKBP6 (K-12) - sc-104248 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-FKBP6 antibody - ab130486 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 antibody - ab169489 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-FKBP6 antibody [EPR3673] - ab108419 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3673

Anti-FKBP6 antibody [EPR3674] - ab92475 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3674

Anti-FKBP6 Antibody (aa256-284, APC) - LS-C257307 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (aa256-284, AP) - LS-C257306 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (aa256-284, Biotin) - LS-C257308 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (aa256-284, PE) - LS-C257311 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (aa255-284) - LS-C321395 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (aa151-200) - LS-C31945 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (clone 8F10) - LS-C198570 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 8F10

Anti-FKBP6 Antibody (aa256-284) - LS-C166166 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (clone AT9B7) - LS-C200858 from LifeSpan Bioscience Prices $315.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone AT9B7

Anti-FKBP6 Antibody (C-Terminus, clone EPR3674) - LS-C105755 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3674

Anti-FKBP6 Antibody - LS-C346183 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (Internal, clone EPR3673) - LS-C138019 from LifeSpan Bioscience Prices $450.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR3673

Anti-FKBP6 Antibody (aa256-284, Azide-free, HRP) - LS-C257310 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 Antibody (aa256-284, FITC) - LS-C257309 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

FKBP6 Antibody - NBP1-54606 from Novus Biologicals Prices $139.00, $299.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

FKBP6 Antibody - NBP2-38905 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

FKBP6 Antibody (8F10) - H00008468-M01-100ug from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 8F10

FKBP6 Polyclonal Antibody - bs-7126R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-FKBP6 antibody produced in rabbit - HPA043046 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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