| Gene Symbol | tbpl1 |
|---|---|
| Entrez Gene | 399086 |
| Alt Symbol | tlf |
| Species | Xenopus |
| Gene Type | protein-coding |
| Description | TBP-like 1 |
| Other Description | TATA box-binding protein-like protein 1|TATA box-binding protein-related factor 2|TBP-like factor|TBP-like protein 1|TBP-related factor 2|xlTLF |
| Swissprots | Q5EAV8 Q9W6Z2 |
| Accessions | Q9W6Z2 AJ238441 CAB41487 BC090226 AAH90226 NM_001090263 NP_001083732 |
| Function | Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box (By similarity). Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis. Particularly regulates genes that have a role in catabolism. {ECO:0000250, ECO:0000269|PubMed:17703192}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Tissue Specificity | Expressed ubiquitously with highest expression in the ovary and testis. {ECO:0000269|PubMed:16412700}. |
| Top Pathways | Herpes simplex infection, Basal transcription factors |
Recombinant Xenopus laevis TATA box-binding protein-like protein 1(tbpl1) - CSB-YP894787XBE CSB-EP894787XBE CSB-BP894787XBE CSB-MP894787XBE from Cusabio
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TATA box-binding protein-like protein 1 (tbpl1), Recombinant Protein - MBS1389573 from MyBioSource
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