Gene Symbol | Bsn |
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Entrez Gene | 12217 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | bassoon |
Other Description | presynaptic cytomatrix protein|protein bassoon |
Swissprots | Q6ZQB5 O88737 E9QMZ3 |
Accessions | CAA76598 EDL21270 O88737 AI836567 AK010775 AK129141 BAC97951 AK135719 BAE22627 AK160649 BAE35940 BC119581 BY742476 XM_006511634 XP_006511697 NM_007567 NP_031593 |
Function | Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses (By similarity). Involved in the formation of the retinal photoreceptor ribbon synapses. {ECO:0000250, ECO:0000269|PubMed:12628168, ECO:0000269|PubMed:12628169}. |
Subcellular Location | Cytoplasm. Cell junction, synapse, synaptosome. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density. |
Tissue Specificity | Expressed in brain and retina. {ECO:0000269|PubMed:12628168, ECO:0000269|PubMed:12628169}. |
bassoon CRISPR/Cas9 KO Plasmid (m) - sc-419370 from Santa Cruz Biotechnology
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bassoon HDR Plasmid (m) - sc-419370-HDR from Santa Cruz Biotechnology
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bassoon Double Nickase Plasmid (m) - sc-419370-NIC from Santa Cruz Biotechnology
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bassoon Double Nickase Plasmid (m2) - sc-419370-NIC-2 from Santa Cruz Biotechnology
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bassoon CRISPR Activation Plasmid (m) - sc-419370-ACT from Santa Cruz Biotechnology
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bassoon CRISPR Activation Plasmid (m2) - sc-419370-ACT-2 from Santa Cruz Biotechnology
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bassoon Lentiviral Activation Particles (m) - sc-419370-LAC from Santa Cruz Biotechnology
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bassoon Lentiviral Activation Particles (m2) - sc-419370-LAC-2 from Santa Cruz Biotechnology
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bassoon siRNA (m) - sc-42169 from Santa Cruz Biotechnology
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bassoon shRNA Plasmid (m) - sc-42169-SH from Santa Cruz Biotechnology
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bassoon shRNA (m) Lentiviral Particles - sc-42169-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN27728 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27728 from Sigma-Aldrich
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BSN siRNA (Mouse) - CRM0420 from Cohesion Biosciences
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BSN - MBS8209306 from MyBioSource
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shRNA set against Mouse BSN (NM_007567.2) - SHH247970 from Creative biogene
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shRNA set against Mouse Bsn(NM_007567.2) - SHG105987 from Creative biogene
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Mouse BSN siRNA - orb279896 from Biorbyt
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BSN shRNA Plasmid (Mouse) - CHM0420 from Cohesion Biosciences
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BSN miRNA 3'UTR clone - MiUTR1M-02288 from Creative biogene
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