GABRB3

Gene Symbol GABRB3
Entrez Gene 2562
Alt Symbol ECA5
Species Human
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor, beta 3
Other Description GABA-alpha receptor beta-2 subunit|GABAA receptor beta-3 subunit|gamma-aminobutyric acid A receptor beta 3|gamma-aminobutyric acid receptor subunit beta-3
Swissprots B7Z2W1 F5H3D2 B7Z825 Q96FM5 P28472 Q14352 H7BYV8
Accessions AAA52507 AAA52508 EAW57653 EAW57654 EAW57655 P28472 AK056018 AK095011 AK295167 BAH11997 AK302822 BAH13811 AK315311 BAG37715 AL120032 AW294342 BC010641 AAH10641 BC038837 BE220174 BE783170 CB162957 CD013894 CD652458 CR747353 DA138788 DB479831 DN994054 DQ891086 ABM82012 EU176555 ABW03356 KJ534842 AHW56482 M82919 AAA52511 XM_011521428 XP_011519730 NM_000814 NP_000805 NM_001191320 NP_001178249 NM_001191321 NP_001178250 NM_001278631 NP_001265560 NM_021912 NP_068712 NR_103801
Function Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel. {ECO:0000269|PubMed:18281286, ECO:0000269|PubMed:18514161, ECO:0000269|PubMed:22243422, ECO:0000269|PubMed:22303015, ECO:0000269|PubMed:24909990}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction

GABA A Rβ3 (C-20) - sc-7364 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GABA<sub>A</sub> Rβ3 (C-20): sc-7364. Western blot analysis of GABA<sub>A</sub> Rβ3 expression in human GABA<sub>A</sub> Rβ3 transfected: sc-111141 (A) and non-transfected: sc-110760 (B) 293 whole cell lysates.

GABA A Rβ3 (V-17) - sc-31430 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GABA<sub>A</sub> Rβ3 (V-17): sc-31430. Western blot analysis of GABA<sub>A</sub> Rβ3 expression in EOC 20 whole cell lysate.

GABA A Rβ3 (D-16) - sc-31431 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GABA A Receptor beta 3 antibody - ab66430 from Abcam

Prices $373.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GABA A Receptor beta 3 antibody - ab125302 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of GABA A Receptor beta 3 staining in Human hippocampus formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab104659, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-GABA A Receptor beta 3 antibody - ab80403 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab80403, at 1/10 dilution, staining GABA A Receptor beta 3 in human lung carcinoma by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue, followed by a peroxidase-conjugated secondary antibody and DAB staining.

Anti-GABA A Receptor beta 3 antibody - ab4046 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
GABA A Receptor beta 3 Antibody [ab4046] - 5-7 ug of mouse cerebellum lysates from wild type (Control) and ß3 knockout (ß3 K/O) animals showing specific immunolabeling of the ~53k ß3-subunit of the GABAA-R in the wild type but not in the ß3 K/O animals

Anti-GABA A Receptor beta 3 antibody [S87-25] - ab98968 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25
ab98968 staining GABA A Receptor beta 3 in Mouse brain tissue sections by Immunohistochemistry (IHC-Fr - frozen sections).

Anti-GABRB3 Antibody (C-Terminus) - LS-C15291 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-GABRB3 Antibody (N-Terminus) - LS-C144761 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GABRB3 Antibody (clone S87-25) - LS-C153148 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (N-Terminus) - LS-C153454 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 594) - LS-C227790 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 390) - LS-C227789 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 488) - LS-C227792 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 565) - LS-C227791 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 655) - LS-C227794 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 633) - LS-C227793 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 680) - LS-C229892 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, AP) - LS-C229894 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, SA) - LS-C227795 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Atto 700) - LS-C229893 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, APC) - LS-C229895 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, Biotin) - LS-C229896 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25

Anti-GABRB3 Antibody (aa370-433, clone S87-25, FITC) - LS-C229897 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S87-25
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