Gene Symbol | Ccl11 |
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Entrez Gene | 20292 |
Alt Symbol | Scya11, eotaxin |
Species | Mouse |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 11 |
Other Description | C-C motif chemokine 11|eosinophil chemotactic protein|eotaxin|small chemokine (C-C motif) ligand 11|small inducible cytokine A11|small-inducible cytokine A11 |
Swissprots | P48298 |
Accessions | AAC53321 EDL15659 P48298 AF128205 AAF22546 AF128206 AAF22547 AF128207 AAF22548 AF128208 AAF22549 AF128209 AAF22550 AK009307 AK010146 BAB26731 AW986913 BC027521 AAH27521 BE200119 U26426 AAC52256 U40672 AAA99776 NM_011330 NP_035460 |
Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed constitutively in the thymus. Expression inducible in the lung (type I alveolar epithelial cells), intestine, heart, spleen, kidney. |
Top Pathways | Cytokine-cytokine receptor interaction, Asthma, Chemokine signaling pathway |
eotaxin CRISPR/Cas9 KO Plasmid (m) - sc-422835 from Santa Cruz Biotechnology
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eotaxin HDR Plasmid (m) - sc-422835-HDR from Santa Cruz Biotechnology
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eotaxin Double Nickase Plasmid (m) - sc-422835-NIC from Santa Cruz Biotechnology
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eotaxin Double Nickase Plasmid (m2) - sc-422835-NIC-2 from Santa Cruz Biotechnology
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eotaxin CRISPR Activation Plasmid (m) - sc-422835-ACT from Santa Cruz Biotechnology
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eotaxin CRISPR Activation Plasmid (m2) - sc-422835-ACT-2 from Santa Cruz Biotechnology
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eotaxin Lentiviral Activation Particles (m) - sc-422835-LAC from Santa Cruz Biotechnology
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eotaxin Lentiviral Activation Particles (m2) - sc-422835-LAC-2 from Santa Cruz Biotechnology
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eotaxin siRNA (m) - sc-63310 from Santa Cruz Biotechnology
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eotaxin shRNA Plasmid (m) - sc-63310-SH from Santa Cruz Biotechnology
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eotaxin shRNA (m) Lentiviral Particles - sc-63310-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN28225 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND28225 from Sigma-Aldrich
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CCL11 siRNA (Mouse) - CRM3622 from Cohesion Biosciences
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CCL11 - MBS8208140 from MyBioSource
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shRNA set against Mouse CCL11 (NM_011330.3) - SHH257489 from Creative biogene
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shRNA set against Mouse Ccl11(NM_011330.3) - SHG134497 from Creative biogene
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Mouse CCL11 siRNA - orb283098 from Biorbyt
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CCL11 shRNA Plasmid (Mouse) - CHM3622 from Cohesion Biosciences
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CCL11 miRNA 3'UTR clone - MiUTR1M-02662 from Creative biogene
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