Gene Symbol | MKI67 |
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Entrez Gene | 4288 |
Alt Symbol | KIA, MIB-, MIB-1, PPP1R105 |
Species | Human |
Gene Type | protein-coding |
Description | marker of proliferation Ki-67 |
Other Description | antigen KI-67|antigen identified by monoclonal antibody Ki-67|proliferation-related Ki-67 antigen|protein phosphatase 1, regulatory subunit 105 |
Swissprots | P46013 Q5VWH2 |
Accessions | CAA64388 CBX53854 EAW49177 EAW49178 EAW49179 P46013 AJ567755 CAD99005 AJ567756 CAD99006 AJ567757 CAD99007 AK299254 BAG61285 BM699306 BU632619 BU855841 X65550 CAA46519 X65551 CAA46520 XM_006717864 XP_006717927 XM_011539818 XP_011538120 NM_001145966 NP_001139438 NM_002417 NP_002408 |
Function | Thought to be required for maintaining cell proliferation. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22002106}. Nucleus, nucleolus {ECO:0000269|PubMed:22002106}. Chromosome {ECO:0000269|PubMed:22002106}. Note=Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes. |
Ki-67 CRISPR/Cas9 KO Plasmid (h) - sc-400081 from Santa Cruz Biotechnology
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Ki-67 HDR Plasmid (h) - sc-400081-HDR from Santa Cruz Biotechnology
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Ki-67 Double Nickase Plasmid (h) - sc-400081-NIC from Santa Cruz Biotechnology
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Ki-67 Double Nickase Plasmid (h2) - sc-400081-NIC-2 from Santa Cruz Biotechnology
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Ki-67 CRISPR Activation Plasmid (h) - sc-400081-ACT from Santa Cruz Biotechnology
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Ki-67 CRISPR Activation Plasmid (h2) - sc-400081-ACT-2 from Santa Cruz Biotechnology
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Ki-67 Lentiviral Activation Particles (h) - sc-400081-LAC from Santa Cruz Biotechnology
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Ki-67 Lentiviral Activation Particles (h2) - sc-400081-LAC-2 from Santa Cruz Biotechnology
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Ki-67 siRNA (h) - sc-37613 from Santa Cruz Biotechnology
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Ki-67 shRNA Plasmid (h) - sc-37613-SH from Santa Cruz Biotechnology
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Ki-67 shRNA (h) Lentiviral Particles - sc-37613-V from Santa Cruz Biotechnology
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Ki-67/MKI67 RNAi - H00004288-R01 from Novus Biologicals
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MISSION® esiRNA - EHU065891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14375 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14375 from Sigma-Aldrich
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MKI67 siRNA (Human) - CRH2907 from Cohesion Biosciences
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shRNA set against Human Mki67 (NM_002417.4) - SHH342240 from Creative biogene
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Human MKI67 siRNA - orb263409 from Biorbyt
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MKI67 shRNA Plasmid (Human) - CHH2907 from Cohesion Biosciences
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MKI67 miRNA 3'UTR clone - MiUTR4H-TG11739 from Creative biogene
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