Gene Symbol |
Krt1
|
Entrez Gene |
16678
|
Alt Symbol |
Krt-2.1, Krt2-1, Krt86
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
keratin 1
|
Other Description |
67 kDa cytokeratin|CK-1|K1|cytokeratin-1|keratin 86|keratin complex 2, basic, gene 1|keratin, type II cytoskeletal 1|keratin-1|type-II keratin Kb1
|
Swissprots |
Q9D2K8 P04104 Q149E0
|
Accessions |
EDL04021 P04104 AI840489 AK019521 BAB31776 BC108410 BC117842 AAI17843 BC117843 AAI17844 M10937 AAD05191 NM_008473 NP_032499
|
Function |
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000250}.
|