PSMA3

Gene Symbol PSMA3
Entrez Gene 5684
Alt Symbol HC8, PSC3
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) subunit, alpha type, 3
Other Description macropain subunit C8|multicatalytic endopeptidase complex subunit C8|proteasome component C8|proteasome subunit C8|proteasome subunit alpha type-3
Swissprots Q9BS70 P25788 Q86U83 B2RCK6 Q8N1D8
Accessions EAW80715 EAW80716 EAW80717 EAW80718 EAW80719 EAW80720 EAW80721 EAW80722 P25788 AK315158 BAG37603 BC005265 AAH05265 BC029402 AAH29402 BC038990 AAH38990 BG703488 BT006711 AAP35357 BT019715 AAV38520 CF128376 CR456933 CAG33214 D00762 BAA00659 DB520127 DQ892645 ABM83571 DQ895883 ABM86809 NM_002788 NP_002779 NM_152132 NP_687033 NR_038123
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2. {ECO:0000269|PubMed:11350925, ECO:0000269|PubMed:17499743}.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Proteasome

PSMA3 (D4Y9O) Rabbit mAb - 12446 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4Y9O
Western blot analysis of extracts from various cell lines using PSMA3 (D4Y9O) Rabbit mAb.

PSMA3 Antibody - 2456 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using PMSA3 Antibody.

20S Proteasome α3 (H-125) - sc-67340 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
20S Proteasome α3 (H-125): sc-67340. Western blot analysis of 20S Proteasome α3 expression in HEL 92.1.7 (A) and TF-1 (B) whole cell lysates and HeLa nuclear extract (C).

20S Proteasome α3 (A-9) - sc-166205 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
20S Proteasome α3 (A-9): sc-166205. Western blot analysis of 20S Proteasome α3 expression in A549 (A) and JAR (B) whole cell lysates and mouse heart (C) and rat placenta (D) tissue extracts.

20S Proteasome α3 (D-6) - sc-166206 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
20S Proteasome α3 (D-6): sc-166206. Western blot analysis of 20S Proteasome α3 expression in A549 (A) and JAR (B) whole cell lysates and mouse heart (C) and rat placenta (D) tissue extracts.

20S Proteasome α3 (A-17) - sc-54707 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

20S Proteasome α3 (G-17) - sc-54670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Proteasome 20S alpha 3 (phospho S250) antibody - ab79184 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Proteasome 20S alpha 3 (phospho S250) antibody (ab79184) at 1/500 dilutionLane 1 : Extracts from 3T3 cells, treated with EGF (200 ng/ml, 30 minutes) Lane 2 : Extracts from 3T3 cells, treated with EGF (200 ng/ml, 30 minutes) with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Proteasome 20S alpha 3 antibody - ab180784 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat lung tissue labelling Proteasome 20S alpha 3 with ab180784 at 1/200. Magnification: 400x.

Anti-Proteasome 20S alpha 3 antibody - ab55887 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Proteasome 20S alpha 3 antibody [EPR5455] - ab109532 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5455
All lanes : Anti-Proteasome 20S alpha 3 antibody [EPR5455] (ab109532) at 1/1000 dilutionLane 1 : A549 cell lysateLane 2 : JAR cell lysateLane 3 : PC12 cell lysateLane 4 : NIH3T3 cell lysateLysates/proteins at 10 µg per lane.

Anti-Proteasome 20S alpha 3 antibody [MCP257] - ab22668 from Abcam

Prices $359.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone MCP257
Luminograph of human placental proteasome preparation after 2D PAGE followed by blotting onto nitrocellulose and probing with ab22668. Antibody dilution 1:1000 using ECL procedure (1 min exposure).

Anti-PSMA3 Antibody (Val228) - LS-C38459 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMA3 Antibody (N-Terminus) - LS-C47056 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMA3 Antibody (aa205-255) - LS-C289461 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse PSMA3 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug), 293T (T; 50 ug), and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PSMA3 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Anti-PSMA3 Antibody (aa179-228) - LS-C112112 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMA3 antibody LS-C112112 Western blot of 293T cell lysate.

Anti-PSMA3 Antibody (phospho-Ser250) - LS-C199495 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from NIH-3T3 cells treated with EGF 200ng/ml 30', using Proteasome alpha3 (Phospho-Ser250) Antibody. The lane on the right was incubated with synthetic peptide.

Anti-PSMA3 Antibody - LS-C192507 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of PSMA3 pAb in extracts from JAR, A549 and PC12 cells.

Anti-PSMA3 Antibody (clone MCP257) - LS-C343781 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone MCP257

Anti-PSMA3 Antibody (C-Terminus) - LS-C112113 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMA3 antibody LS-C112113 Western blot of Fetal Brain lysate.

Anti-PSMA3 Antibody (Internal, clone EPR5455) - LS-C138525 from LifeSpan Bioscience

Prices $450.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5455
IHC of paraffin-embedded human brain tissue using anti-PSMA3 antibody.

Anti-PSMA3 Antibody (aa1-137) - LS-C186309 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded U87 xenograft using 20S Proteasome alpha3 antibody at 1:100 dilution.

Anti-PSMA3 Antibody - LS-C331382 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded rat lung using PSMA3 antibody at dilution of 1:200 (400x lens).

Proteasome 20S alpha 3 Antibody - NBP1-92293 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Proteasome 20S alpha 3 Antibody [NBP1-92293] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

Proteasome 20S alpha 3 Antibody - NBP1-33537 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Proteasome 20S alpha 3 Antibody [NBP1-33537] - Sample (30 ug of whole cell lysate) A: Molt-4 12% SDS PAGE; antibody diluted at 1:1000.
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