CYP2F1

Gene Symbol CYP2F1
Entrez Gene 1572
Alt Symbol C2F1, CYP2F
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily F, polypeptide 1
Other Description CYPIIF1|cytochrome P450 2F1|cytochrome P450, subfamily IIF, polypeptide 1|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
Swissprots A7KAU6 Q8WWJ2 A7KAV0 P24903 A7KAU9 A7KAU8 A7KAU7 Q32MN5
Accessions AAL69652 ABO41974 ABO41975 ABO41976 ABO41977 ABO41978 ABO41979 ABO41980 EAW57017 EAW57018 P24903 AK296884 BAG59445 AK298082 BAG60369 AK316498 BAH14869 BC109056 AAI09057 BC109057 J02906 AAA52156 XM_006723053 XP_006723116 XM_011526551 XP_011524853 XM_011526552 XP_011524854 XM_011526553 XP_011524855 XM_011526554 XP_011524856 XM_011526555 XP_011524857 XR_430190 XR_935755 XR_935756 NM_000774 NP_000765
Function May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3- methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine. {ECO:0000269|PubMed:1974816}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305|PubMed:10383923}; Peripheral membrane protein {ECO:0000305|PubMed:10383923}. Microsome membrane {ECO:0000269|PubMed:10383923}; Peripheral membrane protein {ECO:0000269|PubMed:10383923}.
Tissue Specificity Expressed in lung. Rarely detected in liver and placenta. {ECO:0000269|PubMed:1974816, ECO:0000269|PubMed:8619884}.
Top Pathways Metabolism of xenobiotics by cytochrome P450

CYP2F1 CRISPR/Cas9 KO Plasmid (h) - sc-404064 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F1 HDR Plasmid (h) - sc-404064-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F1 Double Nickase Plasmid (h) - sc-404064-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F1 Double Nickase Plasmid (h2) - sc-404064-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F1 CRISPR Activation Plasmid (h) - sc-404064-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F1 CRISPR Activation Plasmid (h2) - sc-404064-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F1 Lentiviral Activation Particles (h) - sc-404064-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F1 Lentiviral Activation Particles (h2) - sc-404064-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2F2 siRNA (h) - sc-62182 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP2F2 shRNA Plasmid (h) - sc-62182-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP2F2 shRNA (h) Lentiviral Particles - sc-62182-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP2F1 RNAi - H00001572-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN1805 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1805 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02649 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02649

CYP2F1 siRNA (Human) - CRH1104 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP2F1 - MBS8217149 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CYP2F1 (NM_000774.3) - SHH273309 from Creative biogene

Category siRNA
Species Reactivities Human

Human CYP2F1 siRNA - orb261606 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP2F1 shRNA Plasmid (Human) - CHH1104 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYP2F1 miRNA 3'UTR clone - MiUTR1H-02624 from Creative biogene

Species Reactivities Human
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