BECN1

Gene Symbol	BECN1
Entrez Gene	8678
Alt Symbol	ATG6, VPS30, beclin1
Species	Human
Gene Type	protein-coding
Description	beclin 1, autophagy related
Other Description	ATG6 autophagy related 6 homolog|beclin 1 (coiled-coil, moesin-like BCL2 interacting protein)|beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)|beclin-1|coiled-coil myosin-like BCL2-interacting protein
Swissprots	Q14457 Q9UNA8 O75595 B2R6N7
Accessions	EAW60888 EAW60889 EAW60890 Q14457 AF077301 AAC68653 AF139131 AAD27650 AK223411 BAD97131 AK298619 BAG60798 AK299616 BAG61544 AK312651 BAG35534 BC010276 AAH10276 BI496049 BX647788 DC296896 DQ891633 ABM82559 DQ894823 ABM85749 KC776730 AHF22836 L38932 AAB59573 XM_005257758 XP_005257815 XM_005257759 XP_005257816 XM_005257760 XP_005257817 XM_011525421 XP_011523723 NM_003766 NP_003757
Function	Plays a central role in autophagy (PubMed:23184933). Required for the abcission step in cytokinesis (PubMed:20208530). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense. {ECO:0000269|PubMed:20208530, ECO:0000269|PubMed:23184933, ECO:0000269|PubMed:9765397}.
Subcellular Location	Cytoplasm {ECO:0000250|UniProtKB:O88597}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:19050071}; Peripheral membrane protein {ECO:0000269|PubMed:19050071}. Endosome membrane {ECO:0000269|PubMed:23878393}; Peripheral membrane protein {ECO:0000269|PubMed:23878393}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:23878393}; Peripheral membrane protein {ECO:0000269|PubMed:23878393}. Mitochondrion membrane {ECO:0000269|PubMed:23878393}; Peripheral membrane protein {ECO:0000269|PubMed:23878393}. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). {ECO:0000250|UniProtKB:O88597, ECO:0000269|PubMed:19050071}.
Tissue Specificity	Ubiquitous.
Top Pathways	Regulation of autophagy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BECN1 / Beclin-1 ELISA Kit (Sandwich ELISA) - LS-F7208 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Rat BECN1 / Beclin-1 ELISA Kit (Sandwich ELISA) - LS-F9916 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse BECN1 / Beclin-1 ELISA Kit (Sandwich ELISA) - LS-F10930 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Rat BECN1 / Beclin-1 ELISA Kit (Sandwich ELISA) - LS-F10931 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 0.156-10 ng/ml

Human Beclin 1 ELISA Kit - abx150800 from Abbexa Category ELISA Kit Sensitivity 0.056 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human Beclin 1 ELISA Kit - abx051418 from Abbexa Category ELISA Kit Sensitivity 14 pg/ml Range 45 pg/ml - 2000 pg/ml

Beclin 1 (BECN1), Human, ELISA Kit - SEJ557Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.059ng/mL Range 0.156-10ng/mL

Beclin 1, Human, ELISA Kit - E01B0002 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL,

Beclin-1, BECN1, Human, ELISA Kit - E1025h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Beclin 1, BECN1, Human, ELISA Kit - E-EL-H0564 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Coiled-coil myosin-like BCL2-interacting protein/Beclin 1 (BECN1), Human, ELISA Kit - E01C1217 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Beclin 1, BECN1, Rabbit, ELISA Kit - E-EL-RB1750 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Beclin 1, BECN1, Chicken, ELISA Kit - E-EL-Ch1838 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Beclin 1, BECN1, Porcine, ELISA Kit - E-EL-P1369 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Beclin 1, BECN1, Monkey, ELISA Kit - E-EL-MK0370 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human Beclin 1 ELISA Kit - HB0009 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine Beclin 1 ELISA Kit - AB0009 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human BECN1(Beclin 1) ELISA Kit - E-EL-H0564 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human BECN1(Beclin 1)CLIA Kit - E-CL-H0441 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

Beclin 1, ELISA Kit - MBS733192 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,850.00, $5,340.00 Sizes 48 -strip-wells- (Competitive), 96 -strip-wells- (Competitive), 5x96-strip-wells- (Competitive), 10x96-strip-wells- (Competitive)

Beclin 1, ELISA Kit - MBS007437 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin 1, ELISA Kit - MBS031762 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin 1, ELISA Kit - MBS045842 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin 1, ELISA Kit - MBS737300 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Beclin 1, ELISA Kit - MBS059668 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more