C4BPB

Gene Symbol C4BPB
Entrez Gene 725
Alt Symbol C4BP
Species Human
Gene Type protein-coding
Description complement component 4 binding protein, beta
Other Description C4b-binding protein beta chain
Swissprots Q9BS25 D3DT81 Q5VVR0 P20851 A5JYP8
Accessions ABQ52216 EAW93504 EAW93505 EAW93506 P20851 AK092427 AK293379 BAG56891 AK315137 BC005378 AAH05378 BG568018 BM987840 H63461 JF432656 ADZ15873 L11245 AAA35616 M29964 AAB59520 XM_005273253 XP_005273310 XM_005273254 XP_005273311 XM_005273255 XP_005273312 NM_000716 NP_000707 NM_001017364 NP_001017364 NM_001017365 NP_001017365 NM_001017366 NP_001017366 NM_001017367 NP_001017367
Function Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades, Pertussis

C4BPβ (S-20) - sc-17216 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
C4BPβ (S-20): sc-17216. Western blot analysis of C4BPβ expression in rat ovary tissue extract.

C4BPβ (N-20) - sc-17215 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
C4BPβ (N-20): sc-17215. Western blot analysis of C4BPβ expression in OV-90 whole cell lysate.

Anti-C4 binding protein antibody - ab8788 from Abcam

Prices $392.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal
Image from Pham CT et al, J Biol Chem. 2011 Jan 7;286(1):123-30. Epub 2010 Nov 3, Fig 8. DOI 10.1074/jbc.M110.180760

Anti-C4 binding protein antibody - ab83755 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-C4 binding protein antibody (ab83755) at 1 µg/ml + MCF7 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-C4 binding protein antibody - ab155312 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C4 binding protein antibody (ab155312) at 1/1000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLane 3 : K652 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-C4 binding protein antibody - ab182925 from Abcam

Prices $370.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-C4 binding protein antibody - ab123643 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C4 binding protein antibody (ab123643) at 1/100 dilutionLane 1 : Non-transfected 293 cell lysateLane 2 : 293 cell lysate transiently transfected with C4 binding proteinLysates/proteins at 2 µg per lane.

Anti-C4 binding protein antibody - ab76505 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-C4 binding protein antibody (ab76505) at 5 µg/ml + Immunogen at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-C4 binding protein antibody - ab53894 from Abcam

Host Sheep
Clonality Polyclonal

Anti-C4 binding protein antibody - ab183070 from Abcam

Host Sheep
Clonality Polyclonal

Anti-C4 binding protein antibody [10-07] - ab118876 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 10-07
ab118876, at 5 µg/ml, staining C4 binding protein in formalin fixed, paraffin embedded Human liver tissue by Immunohistochemistry.

Anti-C4 binding protein antibody [EPR17101] - ab199430 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR17101
All lanes : Anti-C4 binding protein antibody [EPR17101] (ab199430) at 1/1000 dilutionLane 1 : Human plasmaLane 2 : Human ovary cancer extract.Lysates/proteins at 20 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-C4BPB antibody - ab105507 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-C4BPB antibody (ab105507) at 0.5 µg/ml + Human fetal liver lysate at 10 µg

Anti-C4BP / C4b-Binding Protein Antibody - LS-C147769 from LifeSpan Bioscience

Prices $380.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-C4BP / C4b-Binding Protein Antibody (clone 10-07) IHC-plus™ - LS-B2251 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 10-07
Anti-C4BP / C4b-Binding Protein antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2251 concentration 5 ug/ml.

Anti-C4BP / C4b-Binding Protein Antibody - LS-C147800 from LifeSpan Bioscience

Prices $380.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-C4BPB / C4BP Beta Antibody - LS-C128305 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-C4BPB / C4BP Beta Antibody - LS-C185017 from LifeSpan Bioscience

Prices $495.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-C4BPB / C4BP Beta Antibody (aa125-153, APC) - LS-C253169 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPB / C4BP Beta Antibody - LS-C191525 from LifeSpan Bioscience

Prices $495.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-C4BPB / C4BP Beta Antibody (aa125-153, Biotin) - LS-C253171 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPB / C4BP Beta Antibody (aa125-153, AP) - LS-C253170 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPB / C4BP Beta Antibody (aa125-153, FITC) - LS-C253172 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPB / C4BP Beta Antibody (aa125-153, Azide-free, HRP) - LS-C253173 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C4BPB / C4BP Beta Antibody (aa18-252, Biotin) - LS-C300614 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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