COQ2

Gene Symbol COQ2
Entrez Gene 27235
Alt Symbol CL640, COQ10D1, MSA1
Species Human
Gene Type protein-coding
Description coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Other Description 4-hydroxybenzoate polyprenyltransferase, mitochondrial|PHB:polyprenyltransferase|coenzyme Q2 homolog, prenyltransferase|para-hydroxybenzoate-polyprenyltransferase, mitochondrial
Swissprots Q1JQ78 O95331 Q684R2 Q96H96
Accessions EAX05927 EAX05928 EAX05929 EAX05930 Q96H96 AF091086 AAC72955 AJ621061 CAF18241 AK023076 AK129583 AK300972 BAG62595 BC008804 AAH08804 BC020728 AAH20728 BC116454 AAI16455 BG699931 BM126596 BQ363759 CR456860 CAG33141 DQ895928 ABM86854 EU176380 ABW03831 HG497051 XM_011531855 XP_011530157 XM_011531856 XP_011530158 XM_011531857 XP_011530159 XM_011531858 XP_011530160 XM_011531859 XP_011530161 XM_011531860 XP_011530162 XM_011531861 XP_011530163 XM_011531862 XP_011530164 XM_011531863 XP_011530165 XM_011531864 XP_011530166 XM_011531865 XP_011530167 XM_011531866 XP_011530168 XM_011531867 XP_011530169 XR_427543 XR_938721 NM_015697 NP_056512
Function Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB. {ECO:0000269|PubMed:15153069}.
Subcellular Location Mitochondrion membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.
Tissue Specificity Widely expressed. Present in all of the tissues tested. Expressed at higher level in skeletal muscle, adrenal glands and the heart. {ECO:0000269|PubMed:15153069}.
Top Pathways Ubiquinone and other terpenoid-quinone biosynthesis

Human COQ2 cDNA clone(NM_015697.7) - CDFH004099 from Creative Biomart

Species Human
Accession NM_015697.7

Human COQ2 ORF Clone(NM_015697.7) - CDCR299975 from Creative Biomart

Species Human
Accession NM_015697.7

Human COQ2 ORF Clone(NM_015697.7) - CDCR299977 from Creative Biomart

Species Human
Accession NM_015697.7

Human COQ2 ORF clone(NM_015697.7) - CDCH383818 from Creative Biomart

Species Human
Accession NM_015697.7

Human COQ2 ORF Clone(NM_015697.7) - CDCL159484 from Creative Biomart

Species Human
Accession NM_015697.7

Human COQ2 ORF Clone(NM_015697.7) - CDCL159485 from Creative Biomart

Species Human
Accession NM_015697.7

Human COQ2 ORF clone (NM_015697.7) - CDCR049690 from Creative biogene

Species Human

Human COQ2 cDNA Clone(NM_015697.7) - CDFH004099 from Creative biogene

Species Human
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