| Gene Symbol | Gdnf |
|---|---|
| Entrez Gene | 14573 |
| Alt Symbol | AI385739 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | glial cell line derived neurotrophic factor |
| Other Description | ATF|astrocyte-derived trophic factor|glial cell line-derived neurotrophic factor|mGDNF|neurotrophic factor |
| Swissprots | P97920 P70446 Q6LEL9 P97919 P48540 O09058 |
| Accessions | AAB07463 AAB52953 BAA13591 BAB12221 EDL03340 EDL03341 P48540 BC119031 AAI19032 CJ061678 CJ093961 D49921 BAA08660 D88264 BAA13566 U37459 AAB18672 U66196 U75532 AAB18343 NM_001301332 NP_001288261 NM_001301333 NP_001288262 NM_001301357 NP_001288286 NM_010275 NP_034405 |
| Function | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Expressed in both the central nervous system (CNS) and in non-CNS tissues. Expressed in a highly dynamic pattern in the anterior neuroectoderm during the early stages of neurogenesis between E7.5 and E10.5. Beginning at E10.5, expression begins in mesenchymal tissues of several organs including the digestive tract, kidney, testis, frontonasal mass, tooth primordium, tongue, mandible, whisker follicles, ear, eye, limb bud and in distinct regions of the brain. Also expressed in the heart, ileum, liver and muscle. {ECO:0000269|PubMed:12168040, ECO:0000269|PubMed:8808409}. |
Mouse Gdnf ORF Clone(NM_010275.2) - CDCR248720 from Creative Biomart
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Mouse Gdnf ORF Clone(NM_010275.2) - CDCR248721 from Creative Biomart
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Mouse Gdnf ORF Clone(NM_010275.2) - CDCL164516 from Creative Biomart
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Human Gdnf ORF clone (NM_010275.2) - CDCL111195 from Creative biogene
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