| Gene Symbol |
ATP6V1E2
|
| Entrez Gene |
90423
|
| Alt Symbol |
ATP6E1, ATP6EL2, ATP6V1EL2, VMA4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
|
| Other Description |
V-ATPase subunit E 2|V-type proton ATPase subunit E 2|vacuolar proton pump subunit E 2|vacuolar-type proton-translocating ATPase subunit E1
|
| Swissprots |
Q96A05
|
| Accessions |
AAY14833 EAX00253 Q96A05 AB074759 BAC00847 AK058055 BAB71643 BC008981 AAH08981 BC034808 AAH34808 BG717423 HQ447099 ADQ31586 XM_005264633 XP_005264690 XM_005264634 XP_005264691 XM_011533148 XP_011531450 XM_011533149 XP_011531451 XM_011533150 XP_011531452 XM_011533151 XP_011531453 XM_011533152 XP_011531454 XM_011533153 XP_011531455 XR_939738 XR_939739 NM_080653 NP_542384
|
| Function |
Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Testis specific. {ECO:0000269|PubMed:12036578}.
|
| Top Pathways |
Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis
|