ATIC

Gene Symbol ATIC
Entrez Gene 471
Alt Symbol AICAR, AICARFT, HEL-S-70p, IMPCHASE, PURH
Species Human
Gene Type protein-coding
Description 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Other Description 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase|AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme|AICARFT/IMPCHASE|bifunctional purine biosynthesis protein PURH|epididymis secretory sperm binding protein Li 70p|phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Swissprots Q13856 P31939 E9PBU3 A8K202 Q53S28
Accessions AAY24062 EAW70523 EAW70524 EAW70525 EAW70526 EAW70527 EAW70528 EAW70529 P31939 AA494525 AB062403 BAB93490 AK290067 BAF82756 AK298142 BAG60418 AK313066 BAG35895 BC008879 AAH08879 D82348 BAA11559 D89976 BAA21762 DA043224 DA074758 DQ893262 ABM84188 DQ896591 ABM87590 EU794654 ACJ13708 U37436 AAA97405 NM_004044 NP_004035
Function Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. {ECO:0000269|PubMed:14966129}.
Top Pathways Purine metabolism, One carbon pool by folate

AICAR transformylase (C-19) - sc-49873 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AICAR transformylase (C-19): sc-49873. Immunoperox-idase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

AICAR transformylase (F38 P7 H9) - sc-53612 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AICAR transformylase (F38 P7 H9): sc-53612. Western blot analysis of AICAR transformylase expression in COLO 320DM (A), HCT 116 (B), HeLa (C) and CCRF-CEM (D) whole cell lysates.

AICAR transformylase (H-270) - sc-68421 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AICAR transformylase (H-270): sc-68421. Western blot analysis of AICAR transformylase expression in non-transfected 293T: sc-117752 (A), mouse AICAR transformylase transfected 293T: sc-118294 (B) and COLO 320DM (C) whole cell lysates.

AICAR transformylase (H-3) - sc-365402 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AICAR transformylase (H-3): sc-365402. Western blot analysis of AICAR transformylase expression in CCRF-CEM whole cell lysate.

AICAR transformylase (I-16) - sc-49875 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AICAR transformylase (I-16): sc-49875. Western blot analysis of AICAR transformylase expression in non-transfected: sc-117752 (A) and human AICAR transformylase transfected: sc-159965 (B) 293T whole cell lysates.

AICAR transformylase (N-17) - sc-49876 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AICAR transformylase (N-17): sc-49876. Western blot analysis of AICAR transformylase expression in non-transfected: sc-117752 (A) and human AICAR transformylase transfected: sc-159965 (B) 293T whole cell lysates.

Anti-ATIC antibody - ab186725 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human thyroid cancer tissue labelling ATIC with ab186725 at 1/200. Magnification: 400x.

Anti-ATIC antibody [3H12-C9-H9] - ab131183 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H12-C9-H9
All lanes : Anti-ATIC antibody [3H12-C9-H9] (ab131183) at 1/1000 dilutionLane 1 : Mouse colon tissue lysateLane 2 : A549 cell lysateLane 3 : A431 cell lysateLane 4 : LNCaP cell lysateLane 5 : Jurkat cell lysateLane 6 : U20S cell lysateLane 7 : Rat liver tissue lysateLane 8 : Mouse kidney tissue lysateLane 9 : Mouse brain tissue lysateLane 10 : HeLa cell lysate

Anti-ATIC antibody [EPR13243-53] - ab188321 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13243-53
All lanes : Anti-ATIC antibody [EPR13243-53] (ab188321) at 1/10000 dilutionLane 1 : Jurkat cell lysateLane 2 : HeLa cell lysateLane 3 : HepG2 cell lysateLane 4 : HCT-116 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-AICAR / ATIC Antibody - LS-C178282 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot detection of ATIC in various tissue and cell lysates using ATIC antibody (1:1000 diluted).

Anti-AICAR / ATIC Antibody (aa375-425) - LS-C290912 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human ATIC by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-ATIC antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-AICAR / ATIC Antibody (clone 2C10) - LS-C173847 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C10
Western blot of extracts (35 ug) from 9 different cell lines by using anti-ATIC monoclonal antibody.

Anti-AICAR / ATIC Antibody (clone F38 P7 H9) IHC-plus™ - LS-B1662 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Anti-ATIC antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1662 concentration 15 ug/ml.

Anti-AICAR / ATIC Antibody (clone 4A10) - LS-C173855 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4A10
Western blot of extracts (35 ug) from 9 different cell lines by using g anti-ATIC monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Anti-AICAR / ATIC Antibody (aa310-580) - LS-C185516 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Colon ca using ATIC antibody at 1:100 dilution.

Anti-AICAR / ATIC Antibody (clone 1D2) - LS-C173846 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D2
Western blot of extracts (35 ug) from 9 different cell lines by using anti-ATIC monoclonal antibody.

Anti-AICAR / ATIC Antibody - LS-C334140 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human thyroid cancer using ATIC antibody at dilution of 1:200 (400x lens).

Anti-AICAR / ATIC Antibody - LS-C121361 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-AICAR / ATIC Antibody - LS-C121362 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-AICAR / ATIC Antibody (aa151-200) - LS-C80824 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-AICAR / ATIC Antibody (clone F38 P7 H9) IHC-plus™ - LS-B7299 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Anti-ATIC antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7299 concentration 10 ug/ml.

Anti-AICAR / ATIC Antibody (C-Terminus, clone F38 P7 H9) - LS-C47618 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-AICAR / ATIC Antibody (aa379-428) - LS-C80823 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ATIC antibody LS-C80823 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-AICAR / ATIC Antibody - LS-C27035 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Left and Center: IHC of normal colon tissue and colon carcinoma tissue using ATIC antibody (LS-C27035). Right: Western blot of ATIC antibody on HT29 cell lysate.

Anti-AICAR / ATIC Antibody - LS-C341130 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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