ATIC

Gene Symbol ATIC
Entrez Gene 471
Alt Symbol AICAR, AICARFT, HEL-S-70p, IMPCHASE, PURH
Species Human
Gene Type protein-coding
Description 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Other Description 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase|AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme|AICARFT/IMPCHASE|bifunctional purine biosynthesis protein PURH|epididymis secretory sperm binding protein Li 70p|phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Swissprots Q13856 P31939 E9PBU3 A8K202 Q53S28
Accessions AAY24062 EAW70523 EAW70524 EAW70525 EAW70526 EAW70527 EAW70528 EAW70529 P31939 AA494525 AB062403 BAB93490 AK290067 BAF82756 AK298142 BAG60418 AK313066 BAG35895 BC008879 AAH08879 D82348 BAA11559 D89976 BAA21762 DA043224 DA074758 DQ893262 ABM84188 DQ896591 ABM87590 EU794654 ACJ13708 U37436 AAA97405 NM_004044 NP_004035
Function Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. {ECO:0000269|PubMed:14966129}.
Top Pathways Purine metabolism, One carbon pool by folate