ERG9

Gene Symbol ERG9
Entrez Gene 856597
Alt Symbol -
Species Yeast
Gene Type protein-coding
Description bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase
Other Description -
Swissprots D3DLD8 P29704
Accessions DAA06882 P29704 NM_001179321 NP_012060
Function Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol. May also have a regulatory role regulating the flux of isoprene intermediates through the sterol pathway. Squalene synthase is crucial for balancing the incorporation of farnesyl diphosphate (FPP) into sterol and nonsterol isoprene synthesis. ERG9 is also essential for cell growth in yeast. {ECO:0000269|PubMed:1807826, ECO:0000269|PubMed:2068081, ECO:0000269|PubMed:8323279}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome.
Top Pathways Sesquiterpenoid and triterpenoid biosynthesis, Steroid biosynthesis

Squalene synthase (ERG9), Recombinant Protein - MBS1137923 from MyBioSource

Category Protein
Prices $858.00, $858.00, $870.00, $870.00, $1,090.00, $1,090.00, $1,665.00, $1,665.00, $1,700.00, $2,390.00
Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Yeast

Squalene synthase (ERG9), Recombinant Protein - MBS7014357 from MyBioSource

Category Protein
Prices $1,245.00, $2,235.00, $3,440.00
Sizes 10 µg, 50 µg, 100 µg
Source E Coli
Species Yeast
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