GALE

Gene Symbol GALE
Entrez Gene 2582
Alt Symbol SDR1E1
Species Human
Gene Type protein-coding
Description UDP-galactose-4-epimerase
Other Description UDP galactose-4'-epimerase|UDP-GalNAc 4-epimerase|UDP-GlcNAc 4-epimerase|UDP-N-acetylgalactosamine 4-epimerase|UDP-N-acetylglucosamine 4-epimerase|UDP-galactose 4-epimerase|UDP-glucose 4-epimerase|galactose-4-epimerase, UDP-|galactowaldenase|short chain dehydrogenase/reductase family 1E, member 1
Swissprots Q86W41 Q14376 Q9UJB4 A0A024RAH5 Q9BVE3 Q38G75 B3KQ39
Accessions AAC39645 ABB04109 CBX87741 EAW95083 EAW95084 EAW95085 EAW95086 EAW95087 EAW95088 EAW95089 EAW95090 EAW95091 EAW95092 EAW95093 Q14376 AK057302 BAG51901 AK096127 AK307354 AK314397 BAG37021 AL530475 BC001273 AAH01273 BC050685 AAH50685 BC056880 BI835132 BQ437612 DA043957 DQ233668 ABB04110 DQ891753 ABM82679 DQ894934 ABM85860 L41668 AAB86498 NM_000403 NP_000394 NM_001008216 NP_001008217 NM_001127621 NP_001121093
Function Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6- phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP- GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. {ECO:0000269|PubMed:22654673, ECO:0000303|PubMed:23732289}.
Top Pathways Amino sugar and nucleotide sugar metabolism, Galactose metabolism

GALE (C-4) - sc-390407 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GALE (C-4): sc-390407. Western blot analysis of GALE expression in non-transfected 293T: sc-117752 (A), human GALE transfected 293T: sc-170673 (B) and Caki-1 (C) whole cell lysates.

GALE (D-11) - sc-390460 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GALE (D-11): sc-390460 . Western blot analysis of expression in non-transfected 293T: sc-117752 (A), human GALE transfected 293T: sc-170673 (B) and Caki-1 (C) whole cell lysates.

GALE (E-13) - sc-160058 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GALE (E-13): sc-160058. Western blot analysis of GALE expression in non-transfected: sc-117752 (A) and human GALE transfected: sc-116373 (B) 293T whole cell lysates.

GALE (H-165) - sc-366270 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GALE (H-165): sc-366270. Western blot analysis of GALE expression in non-transfected: sc-117752 (A) and human GALE transfected: sc-116373 (B) 293T whole cell lysates.

GALE (I-12) - sc-160059 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GALE (I-12): sc-160059. Western blot analysis of GALE expression in Hep G2 (A), A549 (B), COS (C), PC-12 (D) and Caki-1 (E) whole cell lysates.

GALE (N-13) - sc-160060 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GALE (N-13): sc-160060. Western blot analysis of GALE expression in non-transfected: sc-117752 (A) and human GALE transfected: sc-110864 (B) 293T whole cell lysates.

Anti-GALE antibody - ab153824 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GALE antibody (ab153824) at 1/500 dilution + A431 whole cell lysate at 30 µg

Anti-GALE antibody - ab67389 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-GALE antibody (ab67389) at 1/500 dilution + Human colon tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-GALE antibody - ab81541 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GALE antibody (ab81541) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-GALE antibody - ab108173 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GALE antibody (ab108173) at 0.5 µg/ml + 293T cell lysate at 10 µg

Anti-GALE antibody [1C4] - ab118033 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C4
All lanes : Anti-GALE antibody [1C4] (ab118033) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY GALE cDNALysates/proteins at 5 µg per lane.

Anti-GALE antibody [EPR11088(B)] - ab155997 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11088(B)
All lanes : Anti-GALE antibody [EPR11088(B)] (ab155997) at 1/10000 dilutionLane 1 : HepG2 cell lysateLane 2 : A375 cell lysateLane 3 : MCF7 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-GALE antibody [EPR11089(B)] - ab155277 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11089(B)
All lanes : Anti-GALE antibody [EPR11089(B)] (ab155277) at 1/1000 dilutionLane 1 : Fetal liver lysateLane 2 : HT29 lysateLane 3 : HepG2 lysateLysates/proteins at 10 µg per lane.

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (clone 1C4) - LS-C172493 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C4
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GALE mouse monoclonal antibody.

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (Internal, AP) - LS-C277506 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (Internal, APC) - LS-C277508 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (Internal, FITC) - LS-C277510 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (Internal, Biotin) - LS-C277509 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (Internal, Azide-free, HRP) - LS-C277511 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (Internal, PE) - LS-C277512 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody - LS-C310434 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody - LS-C307641 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody - LS-C310435 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (Internal) - LS-C327423 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALE / UDP-Glucose 4-Epimerase Antibody (aa201-250) - LS-C117134 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GALE antibody LS-C117134 Western blot of Transfected 293T cell lysate.
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