JMJD7-PLA2G4B

Gene Symbol JMJD7-PLA2G4B
Entrez Gene 8681
Alt Symbol HsT16992, cPLA2-beta
Species Human
Gene Type protein-coding
Description JMJD7-PLA2G4B readthrough
Other Description JMJD7-PLA2G4B protein|jumonji domain containing 7-phospholipase A2, group IVB (cytosolic) read-through
Swissprots P0C869 B4DRT9 Q19KD5 Q19KD6
Accessions EAW92521 AA064721 AB209150 BAD92387 AF065215 AAC78836 AF065216 AF121908 AAD32135 BC013415 BC128426 BC172355 AAI72355 BI768993 BU688449 DA080158 DA096882 DA121536 DQ523799 ABF69195 DQ523800 ABF69196 NM_001198588 NP_001185517 NM_005090 NP_005081 NR_015346
Function Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no activity against phosphatidylcholine. Isoform 5 does have activity against phosphatidylcholine. {ECO:0000269|PubMed:10085124, ECO:0000269|PubMed:10358058, ECO:0000269|PubMed:16617059}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:16617059}.
Tissue Specificity Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas. Isoform 3 is widely expressed. {ECO:0000269|PubMed:10085124, ECO:0000269|PubMed:10358058, ECO:0000269|PubMed:16617059}.
Top Pathways Long-term depression, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels

Recombinant Human PLA2G4B Protein - H00008681-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

JMJD7-PLA2G4B Peptide, Human - M34GP07866H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Recombinant Human JMJD7 Protein, MYC/DDK-tagged - JMJD7-PLA2G4B-788H from Creative Biomart

Category Protein
Source HEK293
Species Human
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