| Gene Symbol |
Bsg
|
| Entrez Gene |
25246
|
| Alt Symbol |
5A11, CE9, EMMPRIN, HT7, Ox47R, basignin
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
basigin (Ok blood group)
|
| Other Description |
Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian)|Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian)|OX-47 antigen|basigin|glycoprotein CE9|neurothelin
|
| Swissprots |
P26453 Q7TNP1
|
| Accessions |
EDL89403 EDL89404 EDL89405 EDL89406 P26453 AY120888 AAM81604 BC059145 AAH59145 BQ199464 CV119278 FQ212571 FQ212582 FQ213065 FQ213626 FQ214193 FQ214232 FQ218399 FQ219910 FQ219990 FQ220920 FQ224837 FQ229144 FQ229755 FQ230014 FQ231850 FQ232262 FQ234420 FQ234809 FQ234829 X54640 CAA38452 X67215 CAA47655 NM_001109882 NP_001103352 NM_012783 NP_036915
|
| Function |
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. {ECO:0000269|PubMed:10921872}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:11719518}; Single-pass type I membrane protein {ECO:0000303|PubMed:11719518}. Melanosome {ECO:0000250|UniProtKB:P35613}. Note=Colocalizes with SLC16A1 and SLC16A8. {ECO:0000250|UniProtKB:P18572}.
|
| Tissue Specificity |
Essentially found in lymphocytes. Also present in various immature cells, endothelia and cells with excitable membranes.
|