CYP3A5

Gene Symbol CYP3A5
Entrez Gene 1577
Alt Symbol CP35, CYPIIIA5, P450PCN3, PCN3
Species Human
Gene Type protein-coding
Description cytochrome P450, family 3, subfamily A, polypeptide 5
Other Description aryl hydrocarbon hydroxylase|cytochrome P450 3A5|cytochrome P450 HLp2|cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5|cytochrome P450-PCN3|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
Swissprots Q53WY8 Q75MV0 A4D289 Q9HB56 B7Z5I7 P20815
Accessions AAB00083 AAG32288 AAK73691 AAS02016 ABG25922 CCQ42992 EAL23868 EAW76638 EAW76639 EAW76640 EAW76641 EAW76642 P20815 AA076026 AF355801 AAK73689 AF355802 AAK73690 AF355804 AJ563378 CAD91347 AJ563379 CAD91649 AK055879 AK223008 BAD96728 AK296205 BAH12282 AK299002 BAH12923 AK309166 AK313813 BAG36549 BC022298 BC025176 BC026255 BC033862 AAH33862 BX537676 CAD97807 BX648856 DC383127 DQ890743 ABM81669 DQ893913 ABM84839 DQ896802 ABM87801 EU176488 ABW03289 J04813 AAA02993 L26985 X90579 XM_006715859 XP_006715922 XM_011515843 XP_011514145 XM_011515844 XP_011514146 XM_011515845 XP_011514147 XM_011515846 XP_011514148 XM_011515847 XP_011514149 XR_927383 NM_000777 NP_000768 NM_001190484 NP_001177413 NM_001291829 NP_001278758 NM_001291830 NP_001278759 NR_033807 NR_033810 NR_033811 NR_033812
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Top Pathways Steroid hormone biosynthesis, Chemical carcinogenesis, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450

CYP3A5 (F18 P3 B6) - sc-53616 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP3A5 (F18 P3 B6): sc-53616. Western blot analysis of human recombinant CYP1A1 (A), CYP2C18 (B), CYP2C19 (C), CYP2D6 (D), CYP4F2 (E), CYP4F3 (F), CYP3A5 (G), CYP3A7 (H) and negative control (I) fusion proteins.

CYP3A5 (D-13) - sc-33247 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP3A5 (D-13): sc-33247. Immunofluorescence staining of formalin-fixed HepG2 cells showing cytoplasmic localization.

Anti-Cytochrome P450 3A5 antibody - ab22692 from Abcam

Prices $372.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-Cytochrome P450 3A5 antibody - ab89811 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Cytochrome P450 3A5 antibody (ab89811) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-Cytochrome P450 3A5 antibody [EPR4396] - ab108624 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4396
Anti-Cytochrome P450 3A5 antibody [EPR4396] (ab108624) at 1/400 dilution (unpurified) + Human fetal liver tissue lysate at 20 µgSecondaryHRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG at 1/1000 dilution

Anti-Cytochrome P450 3A5 antibody [F18 P3 B6] - ab56076 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone F18 P3 B6
All lanes : Anti-Cytochrome P450 3A5 antibody [F18 P3 B6] (ab56076) at 2 µg/mlLane 1 : CYP3A4 recombinant CYP450 proteinLane 2 : CYP3A5 recombinant CYP450 proteinLane 3 : CYP3A7 recombinant CYP450 protein

Anti-Cytochrome P450 3A5 antibody - C-terminal - ab76667 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 3A5 antibody - C-terminal (ab76667) at 1/50 dilution + 293 cell lysate at 35 µg

Anti-CYP3A5 Antibody (aa1-502) - LS-C128496 from LifeSpan Bioscience

Host Mouse
Clonality Polyclonal

Anti-CYP3A5 Antibody (C-Terminus, clone F18 P3 B6) - LS-C140562 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
A. and B. Western blot of 3A5 antibody (LS-C140562) on recombinant CYP450 proteins. C. Immunohistochemistry stain using 3A5 antibody on esophagus cancer tissue.

Anti-CYP3A5 Antibody (Internal, clone EPR4396) - LS-C137869 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone [EPR4396]
IHC of paraffin-embedded human liver tissue using anti-Cytochrome P450 3A5 antibody.

Anti-CYP3A5 Antibody (aa195-224) - LS-C167232 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP3A5 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CYP3A5 Antibody (C-Terminus) - LS-C96732 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CYP3A5 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CYP3A5 Antibody (aa83-132) IHC-plus™ - LS-B11546 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-CYP3A5 Antibody - LS-C331419 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HEK-293 cells lines, using CYP3A5 antibody.

Anti-CYP3A5 Antibody (C-Terminus, clone F18 P3 B6) - LS-C47617 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Cytochrome P450 3A5 Antibody - NBP2-29917 from Novus Biologicals

Prices $299.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Cytochrome P450 3A5 Antibody [NBP2-29917] - Western blot analysis of anti-CYP3A5 Antibody (C-term) in 293 cell line lysates (35ug/lane). CYP3A5 (arrow) was detected using the purified Pab.

Cytochrome P450 3A5 Antibody - H00001577-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P] - Analysis of CYP3A5 expression in human liver.

Cytochrome P450 3A5 Antibody - H00001577-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01] - CYP3A5 MaxPab polyclonal antibody (B01), Lot # 08066 WULz. Western Blot analysis of CYP3A5 expression in human liver.

ANTI-CYP3A5 (CENTER) antibody produced in rabbit - SAB1307210 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP3A5 (Center): <B>Cat. No. SAB1307210</B>: Western blot analysis of CYP3A5 Antibody (Center) in 293 cell line lysates (35 μg/lane).

Monoclonal Anti-Cytochrome P450 3A5 antibody produced in mouse - C4743 from Sigma-Aldrich

Prices $59.70, $389.50
Sizes 25 µl, 200 µl
Host Mouse
Clonality Monoclonal
Clone F18 P3 B6
<B>Immunoblotting</B><BR/>Human recombinant Cytochrome P450 3A5 protein was separated on SDS-PAGE and blotted with Monoclonal Anti-Cytochrome P450 3A5 (<B>Cat. No. C4743</B>). The antibody was developed with Goat Anti-Mouse IgG, Peroxidase conjugate (<B>Cat. No. A2304</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1: 0.5 μg/mL antibody<BR/>2: 0.1 μg/mL antibody<BR/>3: 0.02 μg/mL antibody

Anti-CYP3A5 antibody produced in mouse - SAB1405689 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP3A5: <B>Cat. No. SAB1405689</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~57.1 kDa using human liver lysate.

ANTI-CYP3A5(C-TERMINAL) antibody produced in rabbit - SAB1307237 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP3A5 (C-term): <B>Cat. No. SAB1307237</B>: Western blot analysis of Anti-CYP3A5 (C-term) in 293 cell line lysates (35 μg/lane).

CYP3A5 antibody - N-terminal region (ARP60135_P050) - ARP60135_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CYP3A5-Antibody-Center - AP7794c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CYP3A5 Antibody (Center) (Cat. #AP7794c) in 293 cell line lysates (35ug/lane). CYP3A5 (arrow) was detected using the purified Pab.

CYP3A5-Antibody-C-term - AP7794b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from SK-BR-3 cell line, using CYP3A5 Antibody (C-term) (Cat. #AP7794b). AP7794b was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
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