| Gene Symbol |
Il6r
|
| Entrez Gene |
24499
|
| Alt Symbol |
IL6R1, Il6ra
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
interleukin 6 receptor
|
| Other Description |
IL-6 receptor subunit alpha|IL-6R 1|IL-6R subunit alpha|IL-6R-alpha|IL-6RA|interleukin 6 receptor, alpha|interleukin-6 receptor subunit alpha
|
| Swissprots |
P22273
|
| Accessions |
EDM00609 P22273 CB778659 M58587 AAA41431 XM_006232587 XP_006232649 XM_006232588 XP_006232650 XM_008761127 XP_008759349 NM_017020 NP_058716
|
| Function |
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD)
|