GABRP

Gene Symbol GABRP
Entrez Gene 2568
Alt Symbol -
Species Human
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor, pi
Other Description GABA(A) receptor subunit pi|GABA(A) receptor, pi|gamma-aminobutyric acid receptor subunit pi
Swissprots O00591 D3DQL2 A8KA36 Q32MJ1
Accessions AAC24194 CAM83950 EAW61466 EAW61467 EAW61468 O00591 AK055205 BAG51486 AK292901 BAF85590 AK296805 BAG59378 AK300303 BAG62056 AL708685 BC074810 AAH74810 BC074865 AAH74865 BC109105 AAI09106 BC109106 AAI09107 DC346374 U95367 AAC51357 XM_005265872 XP_005265929 XM_011534502 XP_011532804 XM_011534503 XP_011532805 XM_011534504 XP_011532806 XM_011534505 XP_011532807 XM_011534506 XP_011532808 NM_001291985 NP_001278914 NM_014211 NP_055026
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue Specificity Most abundant in the uterus, also expressed in lung, thymus and prostate.
Top Pathways GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction

GABA A Rπ siRNA (h) - sc-43788 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GABA A Rπ shRNA Plasmid (h) - sc-43788-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GABA A Rπ shRNA (h) Lentiviral Particles - sc-43788-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU028481 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9057 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9057 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10386 from Sigma-Aldrich

Category miRNA

GABRP siRNA (Human) - CRH1706 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GABA-A R pi RNAi - H00002568-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GABRP - MBS8220610 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GABRP (NM_014211.2) - SHH298605 from Creative biogene

Category siRNA
Species Reactivities Human

Human GABRP siRNA - orb262208 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GABRP shRNA Plasmid (Human) - CHH1706 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GABRP miRNA 3'UTR clone - MiUTR3H-05272 from Creative biogene

Species Reactivities Human
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