KCNJ15
| Gene Symbol | KCNJ15 |
|---|---|
| Entrez Gene | 3772 |
| Alt Symbol | IRKK, KIR1.3, KIR4.2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | potassium channel, inwardly rectifying subfamily J, member 15 |
| Other Description | ATP-sensitive inward rectifier potassium channel 15|inward rectifier K(+) channel Kir1.3|inward rectifier K(+) channel Kir4.2|inward rectifier K+ channel KIR4.2|potassium channel, inwardly rectifying subfamily J member 15|potassium inwardly-rectifying channel, subfamily J, member 15 |
| Swissprots | Q99712 Q96L28 D3DSH5 Q99446 O00564 |
| Accessions | EAX09683 EAX09684 EAX09685 Q99712 AI344546 AI453386 AK092958 AK292812 BAF85501 BC013327 AAH13327 BI832561 D87291 BAA13326 DA632853 DA670230 DA673158 DA675388 DA968871 DB008463 DB232867 DQ896861 ABM87860 U73191 AAC50922 Y10745 CAA71734 Y13895 Y13896 XM_005260975 XP_005261032 XM_006724002 XP_006724065 XM_011529560 XP_011527862 XM_011529561 XP_011527863 NM_001276435 NP_001263364 NM_001276436 NP_001263365 NM_001276437 NP_001263366 NM_001276438 NP_001263367 NM_001276439 NP_001263368 NM_002243 NP_002234 NM_170736 NP_733932 NM_170737 NP_733933 |
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
| Top Pathways | Gastric acid secretion |
KIR4.2 CRISPR/Cas9 KO Plasmid (h) - sc-407905 from Santa Cruz Biotechnology
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KIR4.2 HDR Plasmid (h) - sc-407905-HDR from Santa Cruz Biotechnology
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KIR4.2 Double Nickase Plasmid (h) - sc-407905-NIC from Santa Cruz Biotechnology
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KIR4.2 Double Nickase Plasmid (h2) - sc-407905-NIC-2 from Santa Cruz Biotechnology
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KIR4.2 CRISPR Activation Plasmid (h) - sc-407905-ACT from Santa Cruz Biotechnology
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KIR4.2 CRISPR Activation Plasmid (h2) - sc-407905-ACT-2 from Santa Cruz Biotechnology
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KIR4.2 Lentiviral Activation Particles (h) - sc-407905-LAC from Santa Cruz Biotechnology
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KIR4.2 Lentiviral Activation Particles (h2) - sc-407905-LAC-2 from Santa Cruz Biotechnology
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KIR4.2 siRNA (h) - sc-91419 from Santa Cruz Biotechnology
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KIR4.2 shRNA Plasmid (h) - sc-91419-SH from Santa Cruz Biotechnology
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KIR4.2 shRNA (h) Lentiviral Particles - sc-91419-V from Santa Cruz Biotechnology
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KCNJ15 RNAi - H00003772-R01V from Novus Biologicals
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KCNJ15 RNAi - H00003772-R03 from Novus Biologicals
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MISSION® esiRNA - EHU073211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10954 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10954 from Sigma-Aldrich
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KCNJ15 siRNA (Human) - CRH2547 from Cohesion Biosciences
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KCNJ15 RNAi - H00003772-R01 from Novus Biologicals
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KCNJ15 RNAi - H00003772-R02 from Novus Biologicals
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shRNA set against Human KCNJ15 (NM_002243.3) - SHH323251 from Creative biogene
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shRNA set against Human KCNJ15(NM_002243.3) - SHL189532 from Creative biogene
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KCNJ15 shRNA Plasmid (Human) - CHH2547 from Cohesion Biosciences
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KCNJ15 miRNA 3'UTR clone - MiUTR3H-04663 from Creative biogene
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KCNJ15 miRNA 3'UTR clone - MiUTR3H-04664 from Creative biogene
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KCNJ15 miRNA 3'UTR clone - MiUTR3H-04665 from Creative biogene
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