BCOR

Gene Symbol BCOR
Entrez Gene 54880
Alt Symbol ANOP2, MAA2, MCOPS2
Species Human
Gene Type protein-coding
Description BCL6 corepressor
Other Description BCL-6 corepressor|BCL-6 interacting corepressor
Swissprots Q9H233 Q8TEB4 Q6P4B6 Q9H232 Q96DB3 Q9HCJ7 Q6W2J9 Q29RF6 D3DWB4 Q9NXF2 D3DWB3 Q7Z2K7
Accessions EAW59425 EAW59426 EAW59427 EAW59428 EAW59429 EAW59430 Q6W2J9 AB046795 BAB13401 AF317391 AAG41429 AF317392 AAG41430 AK000292 BAA91061 AK056538 AK074286 BAB85037 AK095360 BAG53034 AK225581 AL698729 AY316592 AAR08265 BC009675 AAH09675 BC063536 AAH63536 BC114220 AAI14221 BC128387 AAI28388 BC128456 XM_005272616 XP_005272673 XM_005272618 XP_005272675 XM_005272619 XP_005272676 XM_005272620 XP_005272677 XM_006724536 XP_006724599 XM_011543929 XP_011542231 XM_011543930 XP_011542232 XM_011543931 XP_011542233 NM_001123383 NP_001116855 NM_001123384 NP_001116856 NM_001123385 NP_001116857 NM_017745 NP_060215 NM_001130139 NM_020926
Function Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2). {ECO:0000269|PubMed:10898795, ECO:0000269|PubMed:15004558, ECO:0000269|PubMed:18280243, ECO:0000269|PubMed:19578371, ECO:0000269|PubMed:23911289}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10898795}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:10898795}.

BCoR (H-300) - sc-368360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

BCoR (N-19) - sc-68961 from Santa Cruz Biotechnology

Host Goat
Clonality Polyclonal

BCoR (P-18) - sc-68962 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BCOR antibody - ab135801 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-BCOR antibody (ab135801) at 1/50 dilution + 293 cell line lysate at 35 µg

Anti-BCOR antibody - ab88112 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-BCOR antibody (ab88112) at 1 µg/ml + Human colon tissue lysate at 50 µgSecondaryGoat anti-Mouse IgG at 1/5000 dilution

Anti-BCOR antibody - ab5276 from Abcam

Prices $373.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BCOR antibody - ab129777 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BCOR antibody (ab129777) at 1/500 dilutionLane 1 : COLO cell extractLane 2 : COLO cell extract with immunizing peptide

Anti-BCOR antibody - ab135975 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-BCOR antibody (ab135975) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-BCOR Antibody (aa2-14) - LS-C54575 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BCOR Antibody (aa1705-1755) - LS-C288460 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BCOR Antibody - LS-C306534 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-BCOR Antibody (aa1208-1257) - LS-C200182 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using BCOR antibody.

Anti-BCOR Antibody (aa25-75) IHC-plus™ - LS-B11225 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-BCOR antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11225 concentration 2.5 ug/ml.

Anti-BCOR Antibody (aa384-668, clone 4F6) - LS-C340662 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4F6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCOR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCOR.

Anti-BCOR Antibody (aa1231-1280) - LS-C119397 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using BCOR Antibody. The picture on the right is treated with the synthesized peptide.

Anti-BCOR Antibody (aa1107-1137) - LS-C100540 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BCOR Antibody (Center S1122) IHC of formalin-fixed and paraffin-embedded mouse brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the BCOR Antibody (Center S1122) for immunohistochemistry.

Bcl-6 Antibody - NBP2-24952 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

BCOR Antibody - H00054880-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: BCOR Antibody [H00054880-B01] - BCOR MaxPab polyclonal antibody (B01), Lot # 08056 WULz. Western Blot analysis of BCOR expression in human colon.

BCOR Antibody - NB100-1280 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

BCOR Antibody - H00054880-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: BCOR Antibody [H00054880-A01] - BCOR polyclonal antibody (A01), Lot # 051214JC01 Western Blot analysis of BCOR expression in Y-79 ( Cat # L042V1 ).

BCOR Antibody - NB100-87005 from Novus Biologicals

Prices $249.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BCOR Antibody [NB100-87005] - Detection of Human BCoR on HeLa whole cell lysate using NB100-87005. BCoR was also immunoprecipitated by rabbit anti-BCoR antibody NB100-87004.

BCOR Antibody - NBP2-15560 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BCOR Antibody [NBP2-15560] - Sample (30 ug of whole cell lysate) A: HeLa B: HeLa nucleus 5% SDS PAGE gel, diluted at 1:1000.

BCOR Antibody - H00054880-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

BCOR Antibody - NBP1-68235 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: BCOR Antibody [NBP1-68235] - Analysis of extracts from COLO cells, using BCOR Antibody. The lane on the right is treated with the synthesized peptide.

Anti-BCOR antibody produced in mouse - SAB1400590 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-BCOR, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400590</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.
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